Centrifugal microfluidic platform with digital image analysis for parallel red cell antigen typing

Real-time monitoring and actuation of a hybrid siphon valve for hematocrit-independent plasma separation from whole blood

“…This approach aimed to prioritize plasma purity but led to a significant loss of separated plasma for blood samples with hematocrit levels below 60%, especially those below the 30% threshold. In contrast, our innovative strategy achieved a remarkable 75% increase in the volume of separated plasma for blood samples characterized by low hematocrit levels (HCT < 20%), compared to the conventional practice of priming only the initial valve as outlined in eqn (7). This advancement is particularly significant in medical conditions like anemia, where obtaining smaller blood samples for plasma separation is critical.…”

“…The Centrifugal Disc (CD) or Lab On Disc (LOD) is an integrated platform that utilizes various functional units, including pumps, 1,2 valves, 3 and mixers. 4,5 It enables the execution of rapid, precise, and cost-effective parallel testing, specifically designed for a wide range of biomedical applications, 6 including RBC antigen typing, 7 nucleic acid extraction, 8,9 cell isolation, 10 as well as plasma extraction. 11,12 Several types of forces can be used for manipulating the fluids and particles in micro scales.…”

Exploiting halide perovskites for heavy metal ion detection

“…Additionally, factors such as the stability and regenerability of MOFs also need to be addressed. [16][17][18] Therefore, introduction of novel materials with good selectivity, sensitivity and stability into the field of heavy metal ion detection would open up more avenues for related pollution control.…”

Advances in Microfluidics for Single Red Blood Cell Analysis

“…Ding et al reported compact centrifugal microfluidic platform with smartphone-based image processing for parallel RBC antigen typing further improving the imaging technique by introducing machine learning algorithm and achieving 94.10% in the micro-weighted performance evaluation [57].…”