Cerium(IV) ammonium nitrate catalysed facile and efficient synthesis of polyhydroquinoline derivatives through Hantzsch multicomponent condensation

A solvent-free synthesis of polyhydroquinolines via Hantzsch multicomponent condensation catalyzed by nanomagnetic-supported sulfonic acid

“…This method has the following advantages: Magnetic separation can eliminate expensive centrifugation (compared to methods using nano catalysts without magnetic properties 22 ), nano-sized magnetic particles have large specific surface area so adsorption capacity is high, for this reason, the reaction rate increased leading to energy savings. In contrast to other methods, [23][24][25][26][27][28][29][30][31][32][33][34] the products are obtained in a shorter time. These results clearly indicate that nano-g-Fe 2 O 3 -SO 3 H is an efficient, magnetic and reusable acidic catalyst, and the present method is found to be very effective for the synthesis of polyhydroquinoline derivatives.…”

Preparation, characterization and application of novel ionic liquid as an efficient and reusable catalyst for the solvent-free synthesis of hexahydroquinolines

“…To realize the importance of polyhydroquinoline derivatives in the synthesis of various drug sources, many characteristic methods were reported. They include conventional heating [13,14], L-proline [15], various catalysts such as ammonium nitrate (CAN) [16], silica perchloric acid (HClO 4 -SiO 2 ) [17], trimethylsilyl chloride [18], nickel nanoparticle [19], FeF 3 [20], K7[PW11CoO40] [21], p-TSA [22], solar heat [23], hafnium (IV) [24], SBA-Pr-SO 3 H [25], Bakers' yeast [26], and iron (III) trifluoroacetate [27]. The above mentioned subjects encouraged us to synthesize a new ionic liquid with Brønsted acidic property, named as 1-butyl-3-sulfonic acid imidazolium chloride, [Bsim]Cl, for the first time (Scheme 1), and its full characterization was investigated by using FT-IR, 1 H NMR, 13 C NMR, UV as well as mass spectra, thermal gravimetric analysis (TGA) and differential thermal analysis (DTA).…”

Carbon-Based Solid Acid Catalyzed Synthesis of Polyhydroquinoline Derivatives via Hantzsch Reaction Under Solvent-Free Conditions

“…Recently, a number of improved methods have been reported in the literature for the synthesis of polyhydroquinolines which involve the use of microwave irradiation 12 , solar thermal energy 13 , grinding 14 , and also using various catalysts such as ionic liquid 15 , metal triflates 16 , HY-Zeolite 17 , montmorillonite K-10 18 , cerium(IV) ammonium nitrate 19 , HClO 4 -SiO 2 20 , molecular iodine 21 , Yb(OTf) 3 …”