Cervical Alignment of Patients with Basilar Invagination: A Radiological Study

Lin, Junyu; Bao, Minggui; Shen, Lin; Liu, Junhao; Liu, Qi; Li, Ruoyao; Huang, Zucheng; Zhu, Qingan; Zhang, Zhongmin; Ji, Wei

doi:10.1111/os.13212

Cited by 3 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to the prolapse of odontoid into the foramen magnum, the medulla oblongata and spinal cord are compressed which result in neural symptoms in BI patients. The BI patient was found to present a stiffer neck [ 6 ]. We deduced that the BI patient needed to maintain their cervical spine in a certain posture to reduce discomfort.…”

Section: Discussionmentioning

confidence: 99%

“…In the present study, the results indicated that functional muscles were less in BI patients and decreased with age with more obvious trends than control group. Furthermore, our previous study also revealed that BI patients presented the loss of cervical curvature [ 6 ]. Therefore, early exercise on both cervical extensor and flexor muscles is necessary to alleviate fatty infiltration and strengthen muscle function.…”

Section: Discussionmentioning

confidence: 99%

“…Basilar invagination (BI) is known as deformity of the craniocervical junction (CVJ) region with or without clinical neural symptoms [ 1 - 3 ]. Our team conducted a series of research, focused on the changes in skeletal anatomy in BI patients and reported the characteristics of CVJ structures [ 4 - 6 ]. We previously found that the BI patients presented stiffer cervical alignment than the asymptomatic population [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Our team conducted a series of research, focused on the changes in skeletal anatomy in BI patients and reported the characteristics of CVJ structures [ 4 - 6 ]. We previously found that the BI patients presented stiffer cervical alignment than the asymptomatic population [ 6 ]. It was deduced that the cervical muscles might contribute to the consequences.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Morphological Evaluation of the Cervical Muscle in Patients With Basilar Invagination: A Magnetic Resonance Imaging-Based Study

Lin¹,

Xu²,

Zheng³

et al. 2023

Neurospine

Self Cite

View full text Add to dashboard Cite

Objective: To investigate the characteristics of functional muscle and muscle size in patients with basilar invagination (BI) and explore the effects of atlantoaxial dislocation.Methods: Eighty BI patients (BI group) and 80 age- and sex-matched asymptomatic people (control group) were included. Axial T2 magnetic resonance imaging image was used to measure the cross-sectional area (CSA) and functional CSA (FCSA). The sternocleidomastoid (SCM), longus capitis and longus colli (LCap & LC), trapezius (Trap), splenius capitis (SpCap), splenius cervicis (SpC), semispinalis capitis (SSCap), semispinalis cervicis (SSC), multifidus (MS), levator scapulae (LS) and posterior deep layer muscles (PDLM) were evaluated. Correlations between age, atlantodental interval (ADI), Chamberlain distance and muscles were observed.Results: BI group (39.4 ± 18.4 years; 33 males/47 females) exhibited significantly lower FCSA/CSA ratios than the control group in all extensor and flexor muscles, and presented smaller CSAs on the right and left Trap, SSC, LS, SCM, and left LCap & LC. FCSA/CSA ratios were significantly lower in BI patients with dislocation on the right Trap, SpCap, SpC, SSCap, MS, LS, LCap & LC, and PDLM, and the left SSCap, MS, and LCap & LC than in patients without deformity. Additionally, functional muscles of all parameters decreased with age in BI patients. Excluding children, the Trap, SpC, MS, and LS muscle sizes of BI patients tended to increase with age. ADI and Chamberlain distance tended to correlate negatively with FCSA/CSA ratio.Conclusion: The BI patients, especially those with atlantoaxial dislocation, had less functional muscles compared with the control group. Moreover, their functional muscles decreased with age more obviously.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Morphological Evaluation of the Cervical Muscle in Patients With Basilar Invagination: A Magnetic Resonance Imaging-Based Study

Lin¹,

Xu²,

Zheng³

et al. 2023

Neurospine

Self Cite

View full text Add to dashboard Cite

show abstract

Chamberlain's Line Violation in Basilar Invagination Patients Compared with Normal Subjects: A Systematic Literature Review and Meta-Analysis

et al. 2023

View full text Add to dashboard Cite

Novel MRI Signs in Atlantodental Space Predict Reduction Degree of Atlantoaxial Dislocation

Sheng,

Deng,

Huang

et al. 2024

Orthopaedic Surgery

View full text Add to dashboard Cite

ObjectiveThe type of atlantodental space tissue in patients with atlantoaxial dislocation (AAD) can help doctors understand the possibility of reduction before surgery. However, relevant research on this topic is lacking. This study aimed to summarize cases of AAD, classified based on the atlantodental space using magnetic resonance imaging (MRI), and preliminarily explore its impact on the degree of reduction.MethodsPreoperative T2‐weighted MRIs and dynamic digital radiographs of patients who underwent posterior reduction and fixation surgery for congenital AAD between September 2012 and February 2023 were collected. The patients were classified into flexible and inflexible tissue sign groups based on T2‐weighted imaging. Patients with an atlantodental interval < 3 mm on extension digital radiography were considered radiographically reducible. Three radiologists read and recorded the MRI results using standard protocols. Kappa and Fleiss kappa values were used to evaluate intra‐ and inter‐observer agreements for MRI signs and dynamic digital radiography findings. Multivariate logistic regression and receiver operating characteristic curves were used to analyze the relationships between imaging parameters and the reduction degree.ResultsIn total, 118 patients with AAD were included in the analysis. Inter‐observer agreement among the three readers was higher for MRI than for dynamic digital radiography (0.816 vs. 0.668). The intra‐observer consistency for MRI signs was also better than that of dynamic digital radiography. Both the flexible tissue sign and radiographically reducible groups showed a higher rate of satisfactory reduction. However, only the flexible tissue sign showed positive results in the multivariate regression. The receiver operating characteristic curve for MRI signs as a predictor of satisfactory reduction yielded an area under the curve of 0.776 (95% confidence interval, 0.667–0.875, p < 0.0001).ConclusionsNovel MRI signs of the atlantodental space exhibited high inter‐ and intra‐observer agreement. Patients with flexible tissue signs were more likely to achieve satisfactory reduction after direct posterior surgery.

show abstract

Cervical Alignment of Patients with Basilar Invagination: A Radiological Study

Cited by 3 publications

References 33 publications

The Morphological Evaluation of the Cervical Muscle in Patients With Basilar Invagination: A Magnetic Resonance Imaging-Based Study

The Morphological Evaluation of the Cervical Muscle in Patients With Basilar Invagination: A Magnetic Resonance Imaging-Based Study

Chamberlain's Line Violation in Basilar Invagination Patients Compared with Normal Subjects: A Systematic Literature Review and Meta-Analysis

Novel MRI Signs in Atlantodental Space Predict Reduction Degree of Atlantoaxial Dislocation

Contact Info

Product

Resources

About