Cervical insulin‐like growth factor binding protein‐1 (IGFBP‐1) to predict spontaneous onset of labor and induction to delivery interval in post‐term pregnancy

Abstract

IGFBP-1 predicts both spontaneous labor onset and successful induction in post-term pregnancy. Bishop score and cervical length performed equally well.

Usefulness of the insulin‐like growth factor binding protein‐1 bedside test for ruptured fetal membranes

“…considered that cervical phIGFBP‐1 predicted both spontaneous labor onset and successful induction in post‐term pregnancy . In agreement with previous studies we showed that in women with a negative dipstick test the concentrations of IGFBP‐1 and phIGFBP‐1 were higher in term than in preterm pregnancies . In dipstick‐test‐negative women the cervical status did not affect IGFBP‐1 concentrations, regardless of the presence of blood.…”

Insulin‐like growth factor binding protein 1, Bishop score, and sonographic cervical length: tolerability and prediction of vaginal birth and vaginal birth within 24 hours following labour induction in nulliparous women

“…We performed a PubMed search on 7 January 2016 using the search terms ‘insulin growth factor binding protein 1’ OR ‘IGFBP‐1’ AND ‘labor induction’ OR ‘labour induction’, without any limits, which returned 12 articles: only four of these papers that we further discuss below are original reports presenting primary data on IGFBP‐1 as a predictor of inducibility of labour in women with intact membranes …”

“…In a secondary analysis of a randomised controlled trial on prolonged pregnancy in a heterogeneous population of nulliparous and parous women, IGFBP‐1 predicts both spontaneous labor onset and successful induction. Bishop score and cervical length perform equally well …”

Évaluation de la balance bénéfice/risque selon l’âge gestationnel pour induire la naissance en cas de grossesse prolongée

“…Cependant, il est important de noter que toutes les études ayant étudié les facteurs de risque de césarienne après déclenchement du travail chez les patientes ayant une grossesse prolongée [52][53][54][55][56] …”

“…Cependant, la longueur cervicale mesurée par échographie endovaginale ne semble pas avoir une meilleure prédictivité que le score de Bishop pour le taux d'accouchement par les voies naturelles après déclenchement pour grossesse prolongée [53,54] (NP4). L'échographie 3D du col utérin (volume utérin et Doppler 3D) ne semble pas corrélée au taux d'accouchement par les voies naturelles après déclenchement pour grossesse prolongée [54] (NP4).…”