Chaacteristics of Open Field Behavior of Wistar and Sprague-Dawley Rats

Abstract

The open field test (OFT) was carried out on Wistar and Sprague-Dawley rats between the ages of 3 to 20 weeks. At that time, the behavior of each naive rat was observed for two 3-minute periods separated by an interval of 24 h (Day).The OFT scores varied depending on the day and the age.Comparatively higher activity was observed in the extent of ambulation and rearing at 5 weeks old, rearing and preening at 7 weeks old, and preening and defecation at 11 weeks old in the Sprague-Dawley rats compared with the Wistar rats.

High-Fat Diet Enhances Working Memory in the Y-Maze Test in Male C57BL/6J Mice with Less Anxiety in the Elevated Plus Maze Test

“…Additionally, an association between repetitive behavior and sociability has been reported in C57BL/6J mice [35]. However, in contrast to previous studies that included ND conditions, our findings are based on HFD conditions and provide the novel insight for male C57BL/6J mice, suggesting that an HFD correlates with enhanced working memory in the YMZT, as well as with reduced anxiety in the EPMT but not in the OFT [37][38][39][40][41][42][43][44]. Although further studies are necessary to examine how an HFD enhances working memory and simultaneously affects anxiety-like behavior, our findings indicate that the relatively short-term application of an HFD might have beneficial effects for memory function.…”

Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice

“…The openfield test is a classical system that is routinely used to evaluate general locomotor activity and anxietyrelated behaviour of animals (Ramos and Mormede, 1998;Carola et al, 2002;Prut and Belzung, 2003). This paradigm mimics the natural conflict in mice between their tendencies to explore a novel environment and to avoid an open area (Crawley, 1985;Asano, 1986). The open-field apparatus consisted of a square arena (43.2 × 43.2 cm) that was divided into a central and a peripheral zone (central zone coordinates: 3/3, 3/13, 13/3, 13/13) by an infrared photobeam (MED Associates Inc., USA, Vermont).…”

Effect of long-term aspartame (artificial sweetener) on anxiety, locomotor activity and emotionality behavior in Wistar Albino rats

“…In the case of the open field behavior (OFB), it is the conflict between exploration and aversion against open, bright areas that determines animal behavior [22]. The elevated plus maze (EPM) test is one of the most widely used tests for anxiety.…”