Chagas' heart disease: Descriptive analysis of 141 patients in a hospital of Madrid, Spain

Acosta, Irene; Pérez‐Tanoira, Ramón; Prieto-Pérez, Laura; Úbeda, Alfonso Cabello; Álvarez, Beatriz; Atencio, Patricia; Guerrero, Manuel L. Fernández; Roblas, Ricardo Fernández; Orejas, Miguel; Tomàs, Marta; Cariñanos, Irune; Górgolas, Miguel

doi:10.1016/j.tmaid.2020.101690

Cited by 5 publications

(4 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the indeterminate form was the most prevalent (44.9%). The digestive form, either isolated or associated with heart disease, had a prevalence of 11.8%, which is within the range of the mean prevalence of this clinical form (9%-41%) presented in other studies 12 - 15 , 17 , 19 , 20 , 22 . Regarding the cardiac and cardiodigestive forms, the most common cardiac stage was stage A (44.4%), which, if associated with the indeterminate form, would account for 65.8% of the cohort, with normal left ventricular systolic function on the ECG indicating patients with long-term benign prognoses.…”

Section: Discussionsupporting

confidence: 82%

“…This cohort showed a slight predominance of women (52.2%), characterizing a balanced cohort in terms of sex and reflecting the distribution of men and women in the Brazilian population, which is 51% women and 49% men according to the Brazilian Institute of Geography and Statistics. In previous studies, women accounted for 46% to 84% of the total study population 13 - 17 , 20 - 23 , 34 , 36 , 37 .…”

Section: Discussionmentioning

confidence: 93%

“…Studies on the clinical form of CD conducted in urban areas have shown that the cardiac form predominates, with a prevalence ranging from 56% to 66% 12 - 16 , 22 , 23 Few studies have reported a higher incidence of the indeterminate form, varying between 56% and 81.6% 17 , 20 . These differences in the prevalence of clinical forms are attributed to the profile of the healthcare unit.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Hasslocher‐Moreno

Saraiva

Brasil

et al. 2021

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

INTRODUCTION We aimed to describe the sociodemographic, epidemiological, and clinical characteristics of patients with chronic Chagas disease (CD) at an infectious disease referral center. Changes in patient profiles over time were also evaluated. METHODS This retrospective study included patients with CD from November 1986-December 2019. All patients underwent an evaluation protocol that included sociodemographic profile; epidemiological history; anamnesis; and physical, cardiologic, and digestive examinations. Trend differences for each 5-year period from 1986 to 2019 were tested using a nonparametric trend test for continuous and generalized linear models with binomial distribution for categorical variables. RESULTS A total of 2,168 patients (52.2% women) were included, with a mean age of 47.8 years old. White patients with low levels of education predominated. The reported transmission mode was vectorial in 90.2% of cases. The majority came from areas with a high prevalence (52.2%) and morbidity (67.8%) of CD. The most common clinical presentation was the indeterminate form (44.9%). The number of patients referred gradually decreased and the age at admission increased during the study period, as did the patients’ levels of education. CONCLUSIONS The clinical profile of CD is characterized by a predominance of the indeterminate form of the disease. Regarding the patients who were followed up at the referral center, there was a progressive increase in the mean age and a concomitant decrease in the number of new patients. This reflects the successful control of vector and transfusion transmission in Brazil as well as the aging population of patients with CD.

show abstract

Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Hasslocher‐Moreno

Saraiva

Brasil

et al. 2021

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…1 The migratory flux between endemic and non-endemic countries has spread CD worldwide and turned it into a global health problem, especially in countries with little knowledge on CD and its transmission. [2][3][4] The natural progression of CD is divided in acute and chronic phases. The chronic phase is subdivided into indeterminate and determinate forms.…”

Section: Introductionmentioning

confidence: 99%

Cardiac Magnetic Resonance in the Assessment of Chagas Disease and its Complications

Pacheco

Melo

Rochitte

2020

International Journal of Cardiovascular Sciences

View full text Add to dashboard Cite

Chagas disease in Spain

Ramos-Rincón

2021

Medicina Clínica (English Edition)

View full text Add to dashboard Cite

Chagas' heart disease: Descriptive analysis of 141 patients in a hospital of Madrid, Spain

Cited by 5 publications

References 39 publications

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Cardiac Magnetic Resonance in the Assessment of Chagas Disease and its Complications

Chagas disease in Spain

Contact Info

Product

Resources

About