Challenges in renally eliminated medication use: Evaluating cystatin C and serum creatinine eGFR discordance
Brandy N. Hernandez,
Patrick M. Wieruszewski,
Jason N. Barreto
et al.
Abstract:BackgroundAccurately estimating glomerular filtration rate (GFR) is crucial for dosing medications in hospitalized patients. Due to limitations of serum creatinine for GFR estimation, serum cystatin C (CysC) has been explored as an alternative functional kidney biomarker. This study assessed discordance between eGFRCr and eGFRCysC in a large sample of hospitalized patients and examined the frequency of renally eliminated medications affected by eGFR discordance.MethodsThis multisite historical study included a… Show more
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