2019
DOI: 10.1093/ejcts/ezy488
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Change in indication for cardiac resynchronization therapy?

Abstract: Summary Cardiac resynchronization therapy (CRT) has rapidly evolved as a standard therapy for heart failure (HF) patients with ventricular conduction delay. Although in early trials, only patients with sinus rhythm and advanced stages of HF have been candidates for CRT, more recent data have expanded the indications to patients with mild-to-moderate HF and atrial fibrillation and patients in need of antibradycardia pacing with reduced left ventricular function. On the other hand, it is now well… Show more

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Cited by 10 publications
(9 citation statements)
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“…According to the newest ESC guidelines, CRT represents a Class I, Level A recommendation for the treatment of HFrEF, with LVEF under 35%, regardless of the NYHA class, in patients who are still symptomatic, despite OMT, to reduce morbidity and mortality, and especially, to alleviate their complaints and to improve their quality of life [ 1 , 10 , 23 ]. There is research that predicates that the benefits of this therapy are still underutilized [ 9 , 24 ]. All patients included in this study had an indication of Class I for CRT implantation and were referred for this therapy [ 1 , 10 ].…”
Section: Discussionmentioning
confidence: 99%
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“…According to the newest ESC guidelines, CRT represents a Class I, Level A recommendation for the treatment of HFrEF, with LVEF under 35%, regardless of the NYHA class, in patients who are still symptomatic, despite OMT, to reduce morbidity and mortality, and especially, to alleviate their complaints and to improve their quality of life [ 1 , 10 , 23 ]. There is research that predicates that the benefits of this therapy are still underutilized [ 9 , 24 ]. All patients included in this study had an indication of Class I for CRT implantation and were referred for this therapy [ 1 , 10 ].…”
Section: Discussionmentioning
confidence: 99%
“…Longitudinal strain is more reproducible as compared to radial and circumferential strain, and it evaluates the contraction of the longitudinal fibers, which are the first to be affected [ 4 , 6 , 7 ]. In terms of current treatment options, currently, interventional cardiology comes to the aid of these patients employing CRT [ 8 , 9 ]. Patients with left bundle branch block (LBBB) and significant systolic dysfunction, expressed by HF with reduced ejection fraction (HFrEF), can benefit from this course of treatment according to current guidelines [ 1 , 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…The rate of electronic cardiac device implantation, including cardiac resynchronization therapy (CRT) devices, is rising continuously as a result of an increase of the medium life expectancy and in the aging population and also because of the widening of the indication range [1][2][3]. However, studies have shown a disproportionate increase in device-related complications, especially concerning infections.…”
Section: Introductionmentioning
confidence: 99%
“…СРТ является стандартной терапией для пациентов с сердечной недостаточностью с нарушениями внутрижелудочковой проводимости [6]. Обнаружение у пациентов ФП, позволит провести более эффективную профилактику тромбоэмболических осложнений путем назначения антикоагулянтной терапии [7].…”
Section: Introductionunclassified