Changes in Anterior Chamber Parameters with the Pentacam Rotating Scheimpflug and Axial Length Measurements by Ultrasound in Patients Who Use Isotretinoin

Cumurcu, Tongabay; Şener, Serpil; Özsoy, Ercan; Doğanay, Selim

doi:10.3109/02713683.2011.635399

Cited by 11 publications

(10 citation statements)

References 13 publications

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“…Anterior segment reconstructions were produced with 25 single captures in this study. After completing a scan, the Pentacam software constructs a three-dimensional image of the anterior segment and calculates the ante rior chamber parameters (9) . This imaging provides measurements of anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA) width, and pupil size.…”

Section: Patient Assessmentmentioning

confidence: 99%

Refraction and eye anterior segment parameters in schizophrenic patients

Cumurcu¹,

Keser²,

Cumurcu³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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Approved by the following research ethics committee: Institutional Review Board of the Inonu University School of Medicine (31-07-2012/158). ABSTRACTPurpose: To evaluate the difference in terms of refractive errors and anterior segment parameters between schizophrenic patients and healthy volunteers. Methods: This study compared 70 patients (48 men) who were diagnosed with schizophrenia with a control group of 60 (35 men) who were similar in terms of age, gender, education, and socioeconomic level. Anterior segment examination was performed using a Scheimflug system. Axial length and lens thickness (LT) were measured using optic biometry. The following tests were administered to the psychiatric patient group: Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Negative Symptoms (SANS), and Scale for the Assessment of Positive Symptoms (SAPS). Results: Mild myopia was detected in both the schizophrenic and control groups, with no statistically significant difference (p>0.005). Corneal volume (CV), anterior chamber volume (ACV), anterior chamber depth (ACD), and central corneal thickness (CCT) values were lower in the schizophrenic group, and there was a statistically significant between-group difference (p=0. 026, p=0.014, p=0.048, and p=0.005, respectively). LT was greater in schizophrenics, and the difference was found to be statistically significant (p=0.006). A statistically significant negative correlation was found between SAPS and cylinder values (p=0.008). The axial eye length, cylinder value, pupil diameter, mean keratometric value, and anterior chamber angle revealed no statistically significant difference between the groups (p>0.05). Conclusion: No statistically significant difference was detected in terms of refraction disorders between schizophrenics and the healthy control group, while some differences in anterior chamber parameters were present. These results demonstrate that schizophrenics may exhibit clinical and structural differences in the eye.

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Section: Patient Assessmentmentioning

confidence: 99%

Refraction and eye anterior segment parameters in schizophrenic patients

Cumurcu¹,

Keser²,

Cumurcu³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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“…We found a statistically significant increase for only average SimK values and SAIs between the baseline and the first month of isotretinoin treatment with the use of Sirius. Cumurcu et al recorded significant changes in mean keratometry values between baseline and after the 3rd and 6th months of therapy by means of Pentacam [ 11 ]. The increase in keratometry readings of cornea should be considered when calculating the intraocular lens power for patients at early stages of isotretinoin therapy.…”

Section: Discussionmentioning

confidence: 99%

“…We found a significant reduction in the thinnest corneal thickness measured with Sirius between the baseline and the 1st, 3rd, and 6th months of isotretinoin treatment. Similarly, Cumurcu et al found a significant difference between pretreatment values and the 3rd and 6th month values for CCT, as measured with a Pentacam rotating Scheimpflug, in patients treated with isotretinoin [ 11 ]. A value of residual stromal bed thickness below 250 μ m is considered to be a major risk factor for the development of iatrogenic keratectasia in corneal refractive surgery [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris

Yıldırım

Olcucu

Ağca

et al. 2014

Journal of Ophthalmology

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Purpose. We report the effect of isotretinoin on corneal topography, corneal thickness, and biomechanical parameters in patients with acne vulgaris. Method. Fifty-four eyes of 54 patients who received oral isotretinoin for treatment of acne vulgaris were evaluated. All patients underwent a corneal topographical evaluation with a Scheimpflug camera combined with Placido-disk (Sirius), ultrasonic pachymetry measurements, and corneal biomechanical evaluation with an ocular response analyzer at baseline, in the 1st, 3rd, and 6th months of treatment, and 6 months after isotretinoin discontinuation. Results. The thinnest corneal thickness measured with Sirius differed significantly in the 1st, 3rd, and 6th months compared with the baseline measurement; there was no significant change in ultrasonic central corneal thickness measurements and biomechanical parameters (corneal hysteresis and corneal resistance factor) throughout the study. Average simulated keratometry and surface asymmetry index increased significantly only in the first month of treatment according to the baseline. All changes disappeared 6 months after the end of treatment. Conclusion. Basal tear secretion and corneal morphologic properties were significantly influenced during the systemic isotretinoin treatment and the changes were reversible after discontinuation. No statistical important biomechanical differences were found to be induced by isotretinoin.

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“…Pentacam is based on a 180° rotating Scheimpflug camera which can take 12–50 single images to reconstruct the anterior chamber. After completing test, Pentacam software constructs a three-dimensional image of the anterior segment and calculates the anterior chamber parameters [9]. Three measurements were taken from each case by Pentacam.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of Anterior Segment’s Structures in Tilted Disc Syndrome

Özsoy

Gündüz

Demirel

et al. 2016

Journal of Ophthalmology

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Purpose. To evaluate anterior segment's structures by Pentacam in patients with tilted disc syndrome (TDS). Methods. Group 1 included forty-six eyes of forty-six patients who have the TDS. Group 2 including forty-six eyes of forty-six cases was the control group which was equal to the study group in age, gender, and refraction. A complete ophthalmic examination was performed in both groups. All cases were evaluated by Pentacam. The axial length (AL) of eyes was measured by ultrasound. Quantitative data obtained from these measurements were compared between two groups. Results. There was no statistically significant difference for age, gender, axial length, and spherical equivalent measurements between two groups (p = 0.625, p = 0.830, p = 0.234, and p = 0.850). There was a statistically significant difference for central corneal thickness (CCT), corneal volume (CV), anterior chamber angle (ACA), and pupil size measurements between two groups (p = 0.001, p = 0.0001, p = 0.003, and p = 0.001). Also, there was no statistically significant difference for anterior chamber depth (ACD), anterior chamber volume (ACV), and lens thickness (LT) measurements between two groups (p = 0.130, p = 0.910, and p = 0.057). Conclusion. We determined that CCT was thinner, CV was less, and ACA was narrower in patients with TDS. There are some changes in the anterior segment of the eyes with tilted disc.

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Changes in Anterior Chamber Parameters with the Pentacam Rotating Scheimpflug and Axial Length Measurements by Ultrasound in Patients Who Use Isotretinoin

Abstract: Isotretinoin treatment causes statistically significant changes in most anterior segment parameters during treatment.

Cited by 11 publications

References 13 publications

Refraction and eye anterior segment parameters in schizophrenic patients

Refraction and eye anterior segment parameters in schizophrenic patients

Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris

Evaluation of Anterior Segment’s Structures in Tilted Disc Syndrome

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