Changes in Glutathione S-transferase Activity and Total Protein Contents of Labeo rohita

Abstract

Organophosphate pesticide such as chlorpyrifos (CPF) is widely used to kill the various agricultural pests and domestic species (Shittu et al., 2012). Toxicity associated with chlorpyrifos is an alarming threat not only to aquatic animals but also to human health (Xing et al., 2012). Chlorpyrifos induces toxicity by changing the physiological and antioxidant activities of fish (Tripathi and Shasmal, 2010). It also directly affects the nervous system by inhibiting the acetylcholine esterase (AChE) activity and can also amass in tissues of aquatic individuals (Oruc, 2010).Pesticides cause oxidative stress by stimulating the production of reactive oxygen species (ROS) which contain oxygen like OH -, H 2 O 2 and O -2 radicals which