Changes in Heart Rate Variability in Patients with Spleen-Qi Deficiency Syndrome

Olivera-Toro, Agnese; Fossión, Rubén; Li, Lei; López-Gómez, Rosa Estela; López-Espinosa, Emma; Jiménez‐Estrada, Ismael; Quiróz-González, Salvador

doi:10.1016/j.jams.2019.07.002

Cited by 6 publications

(8 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of the present study, which represent a low vagal tone, could be associated with qi deficiency based on the TCM theory, according to a previous study [12]. Moreover, qi deficiency is one of the significant diagnoses made by the traditional Chinese medical acupuncturists for patients with lower back pain [13].…”

Section: Discussionsupporting

confidence: 68%

Heart Rate Variability during Acupuncture Treatment of Lumbosacral Pain

Yang¹,

Litscher²,

Sheng³

et al. 2020

OBM ICM

View full text Add to dashboard Cite

Pain could be directly related to autonomous imbalance. To date, only one scientific work examining heart rate variability (HRV) and heart rate (HR) as the important parameters of autonomous nervous system (ANS) in the context of clinical routine acupuncture treatments for lumbosacral pain conditions is available in the listed databases. The present study aimed to investigate the short-term effects of HRV and HR, during and after the acupuncture needle stimulation in patients with lower back pain. Eighteen patients (mean age + SD: 60.2 ±12.0 years; 15 males and 3 females) were included in the present study. All the investigations were performed at the Privatclinic Lassnitzhoehe, Austria. The trial was conducted and integrated into routine acupuncture therapeutic interventions. Heart rate, as well as heart rate variability, was measured continuously during needle acupuncture. The Keywords Acupuncture; heart rate variability (HRV); low-back pain (LBP); lumbosacral pain; rehabilitation; heart rate (HR); autonomic nervous system (ANS)

show abstract

Section: Discussionsupporting

confidence: 68%

Heart Rate Variability during Acupuncture Treatment of Lumbosacral Pain

Yang¹,

Litscher²,

Sheng³

et al. 2020

OBM ICM

View full text Add to dashboard Cite

show abstract

“…In a recent publication, we found evidence for an altered ANS in another TCM syndrome, the Spleen-Qi Deficiency Syndrome (SQDS), with a similar higher HR, reduced HRV (lower SDNN), increased LF and LF/HF, and a lower HF, possibly due to an increased sympathetic tone and/ or decreased parasympathetic tone, and also producing alterations in intestinal peristalsis, gastrointestinal symptoms, fatigue, with a decrease in attention [8].…”

Section: Hrv As a Biological Marker In Hyperactive Heart Fire And Oth...mentioning

confidence: 85%

“…All study settings were similar to a clinical trial that the authors recently conducted for another TCM syndrome (Olivera-Toro et al [8]). The present research project was a transverse study conducted from August 2017 to July 2018.…”

Section: Study Settingmentioning

confidence: 99%

“…All participants were instructed to rest for 10 min in a seated position before recording the ECG signal. A detailed description of the measurement equipment, recording procedure, and verification and cleaning of the recorded signals can be found in the study by Olivera-Toro et al [8]. The derived normal-to-normal (N-N) heartbeat intervals were analyzed in the time and frequency domain using the Kubios HRV software (version 2.2, Matlab Kuopio, Finland) [33].…”

Section: ) Electrocardiographic (Ecg) Recordings and Heart Rate Varia...mentioning

confidence: 99%

“…Syndrome differentiation plays a crucial role in TCM to establish diagnoses and decide on therapies, such as moxibustion, acupuncture, herbs, and massage; moreover, it consolidates clinical practice with basic theories of TCM [2,4]. Syndrome differentiation is predominantly based on personal experience and interpretation of signs and symptoms by the practitioner [5,6], using usually qualitative (not quantitative) variables [4,7,8], thus constituting a subjective factor in TCM. There is in creasing interest in investigating the biomedical origins of these signs and symptoms to provide a more objective interpretation of TCM in line with evidence-based Western medicine and systematize the relationship between specific signs and symptoms and particular syndromes and diseases [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Heart Rate Variability and Psychometric Analysis in Patients with Hyperactive Heart Fire Syndrome

Martínez¹,

Fossión

Piceno

et al. 2021

J Acupunct Meridian Stud

View full text Add to dashboard Cite

Background: Hyperactive heart fire syndrome is characterized by anxiety, insomnia, dream-disturbed sleep, tongue ulcers, heat in the hands, and palpitations. However, syndrome differentiation is often subjective due to a lack of objective, quantifiable variables. Objectives: To identify changes in heart rate variability (HRV) and psychometric analysis in patients with hyperactive heart fire syndrome. Methods: Healthy controls (n = 33) were compared to patients with hyperactive heart fire syndrome (n = 48) from the Integrative University Clinic of the State University of Ecatepec Valley (CIU-UNEVE). Physiological outcome measures included heart rate (HR), the standard deviation of the normal-to-normal heartbeat intervals (SDNN), low (LF) and high frequency (HF) power, and the LF/HF ratio. Psychometric outcome measures included the Athens Insomnia Scale (AIS) and the Hamilton Anxiety Rating Scale (HARS). Results: Compared to controls, hyperactive heart fire patients had higher HR (9.6 ± 2.62%), LF (22 ± 4.21%) and LF/HF ratio (23 ± 3.14%), and lower SDNN (21 ± 2.33%) and HF (18 ± 4.61%). Patients showed increased anxiety, both with somatic (33 ± 11.2%) and psychic symptoms (39 ± 10.5%) with more difficulty falling asleep (47 ± 9.9%) and diurnal impact of sleep (31 ± 9.6%). Conclusion: Hyperactive heart fire patients may have a sympathovagal imbalance due to a reduced parasympathetic tone and/or adominant sympathetic tone, which may be at the origin of the observed symptoms of insomnia and anxiety.

show abstract

Metabolomics and network pharmacological analysis to explore the mechanism of ginseng treatment for spleen‐qi deficiency

Liu

Cai

et al. 2022

J of Separation Science

View full text Add to dashboard Cite

Ginseng is the main Chinese herbal medicine for tonifying Qi and invigorating the spleen. It has been used to treat spleen‐qi deficiency with good protective effects for thousands of years, however, its biological mechanism has not been fully elucidated. This study aims to explore the mechanism of ginseng in the treatment of spleen‐qi deficiency by using a comprehensive method combining metabolomics and network pharmacological analysis. Gas chromatography‐mass spectroscopy was applied for investigating the changes in urine metabolites in spleen‐qi deficiency rats and after treatment with ginseng. Metabolomics and network pharmacology analysis were applied to screen potential biomarkers and therapeutic targets of ginseng in the treatment of spleen‐qi deficiency, respectively. Molecular docking was employed to further evaluate the docking mode of potential biomarkers and therapeutic target proteins. The results of metabolomics showed that the therapeutic effects of ginseng are mainly related to its regulation of three metabolic pathways. The molecular structure of potential biomarkers and common proteins was further analyzed by molecular docking to verify its effectiveness. Ginseng has good pharmacological effects by controlling key targets of related metabolic pathways, signal pathways, and potential biomarkers.

show abstract

Changes in Heart Rate Variability in Patients with Spleen-Qi Deficiency Syndrome

Cited by 6 publications

References 36 publications

Heart Rate Variability during Acupuncture Treatment of Lumbosacral Pain

Heart Rate Variability during Acupuncture Treatment of Lumbosacral Pain

Heart Rate Variability and Psychometric Analysis in Patients with Hyperactive Heart Fire Syndrome

Metabolomics and network pharmacological analysis to explore the mechanism of ginseng treatment for spleen‐qi deficiency

Contact Info

Product

Resources

About