Changes in hematological and serum biochemical values in jundiá Rhamdia quelen due to sub-lethal toxicity of cypermethrin

Borges, Adriana; Scotti, Luciana; Siqueira, Daniele Rodrigues; Zanini, Rebeca; Amaral, Fernanda do; Jurinitz, Daiane Follmann; Wassermann, G. F.

doi:10.1016/j.chemosphere.2007.05.068

Cited by 119 publications

(78 citation statements)

References 21 publications

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“…Such values corroborate the results obtained in studies performed by Borges (2007) when exposing Silver catfish (Rhamdia quelen) to Cypermethrin. Nevertheless, Begum (2005), when testing Cypermethrin in Walking catfish (Clarias batrachus), reported an increase of ALT values in the animals exposed to the pyrethroid when compared to the control group.…”

Section: Discussionsupporting

confidence: 81%

“…In this study, animals exposed to concentrations of 1.5 and 2.5mg/L of Cypermethrin had neurological, breathing and behavioral changes such as loss of balance, swimming alterations, dyspnea (they kept their mouths and opercula open), upright swimming and sudden spiral swimming movements. Such results corroborate with Polat et al (2002), who tested Cypermethrin in guppies (Poecilia reticulata) and Borges (2007), who tested Cypermethrin in Silver catfish (Rhamdia quelen). Kumar et al (2007), when exposing Channa punctatus to Cypermethrin, also reported such alterations.…”

Section: Discussionsupporting

confidence: 81%

“…Borges (2007) reported hemoglobin increase in Silver catfish (Rhamdia quelen) exposed to Cypermethrin, corroborating with the results of this study with Silver catfish exposed to a concentration of 2.5mg/L of Cypermethrin when compared to the group exposed to a concentration of 1.5mg/L (P<0.01). On the other hand, Dörücü and Girgin (2001) and Das and Mukherjee (2003), when testing Cypermethrin in Common carp (Cyprinus carp) and carp (Labeo rohita), respectively, observed a decrease in the hemoglobin rate in the groups exposed to pyrethroid when compared to the control group.…”

Section: Discussionsupporting

confidence: 81%

“…An increase (P<0.05) in the value of aspartate aminotransferase (AST) was observed in this study, concerning the group exposed to the concentration of 2.5mg of Cypermethrin when compared to the one exposed to the concentration of 0mg/L, corroborating with Begum (2005) and Borges (2007), which have tested Cypermethrin in Walking catfish (Clarias batrachus) and Silver catfish (Rhamdia quelen), respectively.…”

Section: Discussionsupporting

confidence: 69%

“…Borges (2007), by exposing Silver catfish (Rhamdia quelen) to Cypermethrin, obtained the same responses as this study, but used much lower concentrations than the ones used in this study (0.08 to 0.24 ppm). This difference may be related with the animals' gender and size, since Borges used larger and heavier male animals, when compared to the ones used in this study.…”

Section: Discussionsupporting

confidence: 52%

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Clinical, biochemical and haemathological effects in Rhamdia quelen exposed to cypermethrin

Montanha

Fredianelli

Wagner

et al. 2014

Arq. Bras. Med. Vet. Zootec.

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The acute intoxication of Cypermethrin in Silver Catfish (Rhamdia quelen) was evaluated. Animals weighing 56.67±4.43g and measuring 18.92±1.16cm were exposed to sublethal concentrations of Cypermethrin for the species in hydrological conditions during 96 hours. A total of 52 fish divided into three groups were used and received the following concentrations of Cypermethrin: 0 (n=12); 1.5 (n=20) and 2.5 (n=20)mg/L. The intoxicated animals suffered behavioral changes such as loss of balance, swimming alteration, dyspnea, upright swimming and sudden spiral swimming movements. As soon as the 96-hour period was over, a blood collection for hematological and biochemical analyses was performed. A complete haemogram test, plasmatic protein test, albumin, alanine transaminase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase and alkaline phosphatase (ALP) were studied. The values of erythrocytes, hematocrits, haemoglobin, total number of leukocytes, thrombocyte, ALT, AST and ALP changed according to the groups. The results have shown that the environmental contamination by Cypermethrin is toxic to the species.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 69%

Section: Discussionsupporting

confidence: 52%

See 3 more Smart Citations

Clinical, biochemical and haemathological effects in Rhamdia quelen exposed to cypermethrin

Montanha

Fredianelli

Wagner

et al. 2014

Arq. Bras. Med. Vet. Zootec.

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Enzymatic biomarkers as tools to assess environmental quality: A case study of exposure of the honeybee Apis mellifera to insecticides

Carvalho

Belzunces²,

Carvalho

et al. 2013

Enviro Toxic and Chemistry

110

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The present study was intended to evaluate the responses of enzymes in the honeybee Apis mellifera after exposure to deltamethrin, fipronil, and spinosad and their use as biomarkers. After determination of the median lethal doses (LD50), honeybees were exposed at doses of 5.07 ng/bee and 2.53 ng/bee for deltamethrin, 0.58 ng/bee and 0.29 ng/bee for fipronil, and 4.71 ng/bee and 2.36 ng/bee for spinosad (equivalent to 1/10th [LD50/10] and 1/20th [LD50/20] of the LD50, respectively). The responses of acetylcholinesterase (AChE), carboxylesterases (CaEs-1-3), glutathione-S-transferase (GST), catalase (CAT), and alkaline phosphatase (ALP) were assessed. The results showed that deltamethrin, fipronil, and spinosad modulated these biomarkers differentially. For the enzyme involved in the defense against oxidative stress, fipronil and spinosad induced CAT activity. For the remaining enzymes, 3 response profiles were identified. First, exposure to deltamethrin induced slight effects and modulated only CaE-1 and CaE-2, with opposite effects. Second, spinosad exhibited an induction profile for most of the biomarkers, except AChE. Third, fipronil did not modulate AChE, CaE-2, or GST, increased CAT and CaE-1, and decreased ALP. Thus, this set of honeybee biomarkers appears to be a promising tool to evaluate environmental and honeybee health, and it could generate fingerprints to characterize exposures to pesticides.

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Cellular metabolic, stress, and histological response on exposure to acute toxicity of endosulfan in Tilapia (Oreochromis mossambicus)

Kumar

Sharma

Tripathi

et al. 2014

Environmental Toxicology

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Endosulfan is one of the most hazardous organochlorines pesticides responsible for environmental pollution, as it is very persistent and shows bio-magnification. This study evaluated the impact of acute endosulfan toxicity on metabolic enzymes, lysozyme activities, heat shock protein (Hsp) 70 expression, and histopathology in Tilapia (Oreochromis mossambicus). Among the indicators that were induced in dose dependent manner were the enzymes of amino acid metabolism (serum alanine aminotransferase and aspartate aminotransferase), carbohydrate metabolism (serum lactate dehydrogenase), pentose phosphate pathway (Glucose-6-phosphate dehydrogenase) as well as lysozyme and Hsp70 in liver and gill, while liver and gill Isocitrate dehydrogenase (TCA cycle enzyme) and marker of general energetics (Total adenosine triphosphatase) were inhibited. Histopathological alterations in gill were clubbing of secondary gill lamellae, marked hyperplasia, complete loss of secondary lamellae and atrophy of primary gill filaments. Whereas in liver, swollen hepatocyte, and degeneration with loss of cellular boundaries were distinctly noticed. Overall results clearly demonstrated the unbalanced metabolism and damage of the vital organs like liver and gill in Tilapia due to acute endosulfan exposure.

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Changes in hematological and serum biochemical values in jundiá Rhamdia quelen due to sub-lethal toxicity of cypermethrin

Cited by 119 publications

References 21 publications

Clinical, biochemical and haemathological effects in Rhamdia quelen exposed to cypermethrin

Clinical, biochemical and haemathological effects in Rhamdia quelen exposed to cypermethrin

Enzymatic biomarkers as tools to assess environmental quality: A case study of exposure of the honeybee Apis mellifera to insecticides

Cellular metabolic, stress, and histological response on exposure to acute toxicity of endosulfan in Tilapia (Oreochromis mossambicus)

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