Changes in intraocular lens surface roughness during cataract surgery assessed by atomic force microscopy

Strauss, Rupert W.; Hochleitner, Markus E.; Gsenger, Wolfgang; Alge-Priglinger, Claudia S.; Faschinger, Christoph; Henrich, P. B.; Wedrich, Andreas; Priglinger, Siegfried; Schilcher, Kurt

doi:10.1016/j.jcrs.2011.07.028

Cited by 8 publications

(12 citation statements)

References 28 publications

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“…This study looked into the changes in the surface characteristics of preloaded and nonpreloaded IOLs during folding and injection. 10,15 In this study, we found that these surface alterations still occur even with the concurrent use of OVD, and the higher magnification of SEM showed that these alterations represent an actual damage to the optical surface of the lens. In another study, it was found that these scratches happen with the use of forceps for folding, and they reported absence of these scratches if OVD was used during manipulation.…”

Section: Discussionsupporting

confidence: 51%

“…This study looked into the changes in the surface characteristics of preloaded and nonpreloaded IOLs during folding and injection. 10,15…”

Section: Discussionmentioning

confidence: 99%

“…8 Surface alterations of optical surface of foldable acrylic IOL during the process of folding, cartridge engagement, and unfolding have been reported. 9,10 These alterations in the optical surface could play a role in increased surface roughness and hence the growth of lens epithelial cells in vitro. 11,12 The number of cells adhering the intraocular lens optic is reported to be directly related to the roughness of the surface of the optic of the intraocular lens.…”

Section: Introductionmentioning

confidence: 99%

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Scanning electron microscopic characteristics of manually loaded and preloaded foldable acrylic intraocular lenses

Rateb

Eldaly

Ibrahim

et al. 2018

European Journal of Ophthalmology

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Section: Discussionsupporting

confidence: 51%

“…This study looked into the changes in the surface characteristics of preloaded and nonpreloaded IOLs during folding and injection. 10,15…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Scanning electron microscopic characteristics of manually loaded and preloaded foldable acrylic intraocular lenses

Rateb

Eldaly

Ibrahim

et al. 2018

European Journal of Ophthalmology

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“…Furthermore, it was found that hydrophobic acrylic and silicone IOLs had relatively low mean surface roughness values compared with PMMA [10]. Strauss et al [9] also studied the influence of IOL injection through the lens cartridge on the surface roughness of hydrophobic acrylic IOLs. They found that passing these lenses through the injection system had a significant influence on their surface integrity.…”

Section: Discussionmentioning

confidence: 99%

Comparative Surface Imaging Study of Multifocal Diffractive Intraocular Lenses

Son

Lee

Khoramnia

et al. 2021

Klin Monbl Augenheilkd

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Purpose To analyse and compare the surface topography and roughness of three different types of diffractive multifocal IOLs. Methods Using scanning electron microscope (SEM, Inspect F, 5.0 KV, maximum magnification up to 20,000) and atomic force microscope (AFM, Park Systems, XE-100, non-contact, area profile comparison, 10 × 10 µm, 40 × 40 µm), the surface quality of the following diffractive IOLs was studied: the AcrySof IQ PanOptix (Alcon, USA), the AT LARA 829MP (Carl Zeiss Meditec, Germany), and Tecnis Symfony (Johnson&Johnson Vision, USA). The measurements were made over three representative areas (central non-diffractive optic, central diffractive optic, and diffractive step) of each IOL. Roughness profile in terms of mean arithmetic roughness (Ra) and root-mean-squared roughness (Rq) values were obtained and compared statistically. Results In SEM examination, all IOLs showed a smooth optical surface without any irregularities at low magnification. At higher magnification, Tecnis Symfony showed unique highly regular, concentric, and lineate structures in the diffractive optic area which could not be seen in the other studied diffractive IOLs. The differences in the measured Ra and Rq values of the Tecnis Symfony were statistically significant compared to the other models (p < 0.05). Conclusion Various different topographical traits were observed in three diffractive multifocal IOLs. The Ra values of all studied IOLs were within an acceptable range. Tecnis Symfony showed statistically significant higher surface Ra values at both central diffractive optic and diffractive step areas. Furthermore, compared to its counterparts, Tecnis Symfony demonstrated highly ordered, concentric pattern in its diffractive surfaces.

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“…Je nach Konfiguration des Injektors kann es zum Einklemmen der Haptik oder Kratzern auf der Optik kommen [8]. Außerdem konnte in der Vergangenheit eine Erhöhung der Rauheit der IOL-Oberfläche nach Verwendung des Injektors nachgewiesen werden [9].…”

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Sicherheit geht vor – Evaluation von IOL-Injektorsystemen

Borkenstein

2019

Klin Monatsbl Augenheilkd

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Zusammenfassung Hintergrund Der Fortschritt in der Kataraktchirurgie brachte vorgeladene IOL-Implantationssysteme auf den Markt. Diese sollen die OP-Gesamtzeit sicher und effektiv verkürzen. Im Rahmen dieser Studie wurde die Sicherheit und Handlichkeit des 2-Komponenten-Autoloading-Systems SAFELOADER® (HumanOptics AG, Erlangen, Deutschland) bewertet und mit 2 anderen Systemen verglichen. Material und Methoden Insgesamt wurden 167 Augen in die monozentrische prospektive Studie eingeschlossen. In 67 Augen wurden die IOLs durch das SAFELOADER-System, in 50 Augen durch ein Fully-preloaded-System (TECNIS iTec® Preloaded Delivery System, Johnson & Johnson Vision, Santa Ana, CA, USA) und in 50 Augen durch ein manuelles System (UNFOLDER® Platinum 1 Series Delivery System, Johnson & Johnson Vision, Santa Ana, CA, USA) implantiert. Für jedes Verfahren wurden die IOL-Vorbereitungszeit und die Implantationszeit in Sekunden festgehalten. Der OP-Ablauf sowie die Handhabung durch den Arzt und die OP-Schwester wurden bewertet. Ergebnisse Der SAFELOADER und iTec sind schneller und handlicher als der UNFOLDER. Die Vorbereitungszeit des SAFELOADER war mit einem Median von 6,5 Sekunden (s) (5,3 – 6,9) ca. 1 s länger (p < 0,0001) als die des iTec-Systems mit 5,2 s (4,5 – 6,5). Beide waren signifikant (p < 0,0001) schneller als der manuelle UNFOLDER mit 26,9 s (20,6 – 30,1). Bei Betrachtung der reinen Implantationszeit gab es kaum Unterschiede zwischen SAFELOADER mit 7,2 s (5,3 – 8,6), iTec mit 7,3 s (5,9 – 8,3) und UNFOLDER mit 7,2 s (5,9 – 7,6). Im gesamten OP-Ablauf schnitten SAFELOADER mit einer Note von 2,0 (1,0 – 3,0) und iTec 1,0 (1,0 – 3,0) deutlich (p < 0,0001) besser ab als das manuelle System mit 5,0 (3,0 – 5,0). Der Arzt empfand die Handhabung des SAFELOADER und des iTec (beide Median 1,0; 1,0 – 2,0) signifikant (p < 0,0001) besser als die des UNFOLDER (2,5; 1,0 – 4,0). Für die OP-Schwester schnitt der SAFELOADER mit 1,0 (1,0 – 2,0) signifikant (p < 0,0001) besser ab als iTec mit 2,0 (1,0 – 3,0) und der UNFOLDER mit 4,0 (2,0 – 5,0). Schlussfolgerung Das 2-Komponenten-Autoloading-System SAFELOADER® ist intuitiv zu handhaben, schnell und effektiv in der Anwendung und bietet ein hohes Maß an Sicherheit.

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Changes in intraocular lens surface roughness during cataract surgery assessed by atomic force microscopy

Abstract: Standard application procedures of IOLs may alter the IOL surface. Increases in the surface roughness of IOLs may influence postoperative posterior capsule opacification. Further studies are necessary to evaluate the interfacial properties of IOLs.

Cited by 8 publications

References 28 publications

Scanning electron microscopic characteristics of manually loaded and preloaded foldable acrylic intraocular lenses

Scanning electron microscopic characteristics of manually loaded and preloaded foldable acrylic intraocular lenses

Comparative Surface Imaging Study of Multifocal Diffractive Intraocular Lenses

Sicherheit geht vor – Evaluation von IOL-Injektorsystemen

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