2016
DOI: 10.1007/s12562-016-1035-3
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Changes in plasma steroid levels and gene expression of pituitary gonadotropins, testicular steroidogenesis-related proteins and insulin-like growth factors during spermatogenesis of the yellowtail Seriola quinqueradiata

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Cited by 14 publications
(9 citation statements)
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“…To complete the process, enzymes and other proteins are required for biosynthesis (64) . In the present study, the steroid hormone biosynthesis pathway and the key genes 3b-hsd and cyp11a1 were signi cant up-regulated in stage IV testis, indicating the importance of steroidogenesis for spermatogenesis (62,65) . A few pathways related to RNA transcription and translation transportation, namely RNA transport, mRNA surveillance pathway and ubiquitin mediated proteolysis, were also signi cantly enriched in stage IV testis, suggested the metabolism and synthesis under gonadotropin and steroid hormone have been crucial for maintenance of spermatogenesis (62,66) .…”
Section: Key Pathways In Testis Development and Gametogenesis Of Malesupporting
confidence: 54%
“…To complete the process, enzymes and other proteins are required for biosynthesis (64) . In the present study, the steroid hormone biosynthesis pathway and the key genes 3b-hsd and cyp11a1 were signi cant up-regulated in stage IV testis, indicating the importance of steroidogenesis for spermatogenesis (62,65) . A few pathways related to RNA transcription and translation transportation, namely RNA transport, mRNA surveillance pathway and ubiquitin mediated proteolysis, were also signi cantly enriched in stage IV testis, suggested the metabolism and synthesis under gonadotropin and steroid hormone have been crucial for maintenance of spermatogenesis (62,66) .…”
Section: Key Pathways In Testis Development and Gametogenesis Of Malesupporting
confidence: 54%
“…HSD17B1 is also involved in conversion between A-dione and T, raising the further question of how male amberjacks produce their androgens. Upregulation of steroidogenic enzyme expression and elevated plasma 11-ketotestosterone (11-KT) levels are observed annually at the initiation of spermatogenesis in yellowtail [24]. Similar dynamics of plasma T and 11-KT levels are also observed in amberjack [25].…”
Section: Hsd17b1 Is a Cytosolic Protein That Catalyzes Interconversion Of Estrogens (Estrone [E1] And Estradiol [E2]) And Androgens (Andrmentioning
confidence: 90%
“…In fact, this androgen has been proposed as a possible trigger for the onset of puberty in sea bass , suggesting that the unbalanced production of 11-KT regulated by fshβ might be limiting the stimulation of germ cell proliferation at the testicular level, and hence the onset and progression of gametogenesis in juvenile fish , as shown in this study. In yellowtail (Seriola quinqueradiata), 11-KT plays an important physiological role in gonadal development and stimulates early mitotic divisions of spermatogonia toward meiosis (Higuchi et al, 2017). In addition, our results also revealed that LL evoked changes on the plasmatic levels of sex steroids as previously observed in this species and others (Ammar et al, 2015).…”
Section: Capítulo 5 Artículosupporting
confidence: 86%
“…Por lo tanto, estos resultados refuerzan la idea de que los mecanismos regulatorios de síntesis y liberación de esta hormona son diferentes en lubina, como ya se ha sugerido en estudios anteriores . Sin embargo, la disminución observada en los niveles plasmáticos de Fsh durante el periodo fotolábil y la baja precocidad de los individuos, sugiere que en la lubina, al igual que lo observado en otras especies de teleósteos como en la seriola aleta amarilla (Higuchi et al, 2017), la Fsh puede estar jugando un papel importante en etapas tempranas del desarrollo gonadal, bien sea activando la producción de esteroides gonadales o regulando genes muy importantes para el comienzo de la espermatogénesis como ha sido propuesto por Sambroni et al (2013). De hecho, experimentos in vivo en lubina han demostrado que la Fsh, pero no la Lh, es capaz de activar la espermatogénesis en individuos inmaduros , promover la proliferación de células germinales, los niveles plasmáticos de 11-KT y regular genes involucrados en el proceso espermatogénico (Mazón et al, , 2015.…”
Section: Capítulo 7 Discusiónunclassified
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