Changes in Retinal Vessel and Retinal Layer Thickness After Vitrectomy in Retinal Detachment via Swept-Source OCT Angiography

Abstract

Citation: Hong EH, Cho H, Kim DR, Kang MH, Shin YU, Seong M. Changes in retinal vessel and retinal layer thickness after vitrectomy in retinal detachment via swept-source OCT angiography. Invest Ophthalmol Vis Sci. 2020;61(2):35. https://doi.org/10.1167/iovs.61.2.35 PURPOSE.To compare postvitrectomy retinal and choroidal vessel density (VD) and retinal layer thickness between eyes with macula-off and macula-on rhegmatogenous retinal detachment (RRD) using swept-source optical coherence tomography (SS-OCT) and optical coherence tomography angiography (OCTA) and to identify OCTA factors associated with visual outcomes. METHODS.We retrospectively reviewed 31 eyes that underwent pars plana vitrectomy for primary RRD. Eyes with macula-off and macula-on RRD were compared with healthy fellow eyes. Both OCT and OCTA were performed 6 months after surgery, and the maculaoff RRD group was divided into two subgroups according to the presence of an outer retinal defect. The correlations between postoperative best-corrected visual acuity (BCVA) at 6 months and SS-OCT and OCTA measurements were analyzed. RESULTS.Twenty eyes with macula-off RRD and 11 eyes with macula-on RRD were included. In the macula-off RRD group, the central retinal thickness was significantly decreased 6 months postoperatively compared with the fellow eyes (228.9 ± 29.7 μm and 253.6 ± 27.7 μm, P = 0.009). In the outer retinal defect group, the choriocapillaris plexus (CCP) VD was significantly decreased compared with the fellow eyes (56.4% ± 4.8% and 60.2% ± 4.0%, P = 0.026). In the macula-off RRD group, the postoperative BCVA at 6 months correlated significantly with the ratio of the center CCP VD of the detached eyes to that of the fellow eyes (R 2 = 0.207, P = 0.025). CONCLUSIONS.The CCP VD could be related to the anatomical restoration of the outer retinal layer in macula-off RRD. The CCP VD as determined by OCTA could be an indicator of the visual outcome after surgery in macula-off RRD.with macula-off and macula-on RRD using swept-source OCT (SS-OCT) and OCTA and to find OCTA factors related to postoperative visual outcomes.

<p>Functional and Structural Outcomes at the Foveal Avascular Zone with Optical Coherence Tomography Following Macula off Retinal Detachment Repair</p>

“…Table 3 describes a comparison study between this study and some recent literature on a similarly treated group of RRD. [29][30][31] This study has some limitations in its design related due to the small sample size and shorter follow-up compared to some previous studies. Use of silicone oil-based tamponade in all cases may cause some imaging artifacts and can affect post-operative vision.…”

OCT Angiography Findings in Macula-ON and Macula-OFF Rhegmatogenous Retinal Detachment: A Prospective Study

“…Recently, the choriocapillary layer (CCP) was investigated in patients undergoing surgery for RRD repair [ 26 , 27 ]. In macula-OFF patients with an outer retinal defect, CCP vascular density was significantly correlated to VA, hypothesizing that choroidal vascularization can affect the IS/OS segment trophism.…”

Optical Coherence Tomography Angiography following Scleral Buckling Surgery

“…Following vitreo-retinal (VR) surgery in RRD, using SSOCTA, Hong et al (2020) found that the vascular densities in superficial and deep capillary plexus in the detached eyes did not differ significantly from those in the fellow eyes. Their eyes had a short onset duration (of 6-8 days) for RRD before undergoing surgery.…”

“…The central retinal artery forms the superficial capillary plexus (SCP); central retinal artery and choriocapillaris supplying outer plexiform layer form deep capillary plexus (DCP); while the choriocapillaris supply the retinal pigment epithelium, photoreceptor layer, external limiting membrane and outer nuclear layer. The choroidal circulation supplies foveal avascular zone (FAZ) (Hong et al, 2020).…”