Changes in selected hematology and serum biochemistry in Turkish Angora cats (Felis catus) during growth period

Abstract

The purpose of the present study was to determine the changes in selected hematology and serum biochemistry of Angora cats (Felis catus) during growth period. A total of 32 Angora cats (16 adults and 16 kittens) were used in this study. Blood samples were collected from the animals, and were analyzed for white blood cells, red blood cells, hemoglobin, packed cell volume, mean corpuscular volume (MCV), mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, granulocytes, monocytes and lymphocytes numbers. In the serum, alanine aminotransferase, aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT), lactate dehydrogenase (LDH), creatinine kinase (CK), total cholesterol, glucose, triglyceride, urea, creatinine, total protein, albumin, Ca, Mg, Pi levels were determined. Monocyte level was found higher, and ALP, LDH, CK activities and Pi levels were lower in adult cats as compared to the kittens. MCV was lower and GGT and AST activities, and glucose level were higher in kittens of 1.5-3 months old than in kittens of >3 months. Concentrations of total cholesterol and Mg were higher in kitten (1.5-3 months old) than in adult cats. In conclusion, age related effects on hematological and biochemical blood parameters have been determined for the first time in Angora cats.

Some hematological and biochemical parameter levels in healthy Van cats at different age and gender

“…The factors such as glomerular filtration, tubular reabsorption and secretion and total body skeleton muscle store may affect the level of creatinine, again there may be some changes in BUN levels depending on the age and diet, and high level of protein taking increases BUN level in the animals. It is stated that TP and albumin levels may change with the age, the increase in TP levels depending on age may depend on the decrease in body water or increase in the levels of gamma globulin (Simsek et al 2014). In this study, there are some differences between groups in these biochemical parameters in healthy cats but these differences were detected not to be statistically significant.…”

“…In our current study, in young animals in both genders, it has been detected that ALP activities in both groups are higher compared to the other groups, but the difference between them is not statistically significant (Table 4). When compared to the other species, even small changes in ALP activities in cats are important, again in young animals, masculine-based ALP activity is higher, for this reason, it has been stated that ALP activity especially in the animals younger than 6 months is higher than the adult animals (Lawler et al 2006, Simsek et al 2014. It is stated that there may be some changes in serum creatinine, BUN, TP and albumin levels depending on age, gender and various reasons.…”

“…In this study, that the WBC levels are identified on the normal limits mentioned for cats is associated with that the animals are healthy, making parasitic struggles regularly and being careful about not forming stress during bloodletting process. Simsek et al (2014) states that some changes may occur in hematological parameters depending on the age, HGB levels in kittens is lower, their HCT levels increased with age and the reason of this is stated to be associated with higher oxygen carrying capacity of blood in adult cats. Indeed, in the study they made, compared to the cats older than 3 months, in 1.5-3-month cats, WBC levels were stated to be higher, RBC, HGB and PCV levels were stated to be lower.…”

“…Due to age, gender and various reasons, it is stated that some changes can occur in many biochemical parameters (Marco et al 2000, Turgut 2000, Lawler et al 2006, Sonmez and Agaoglu 2010, Simsek et al 2014, some biochemical parameter values in Van cats are different in female, male cats and kittens (Sonmez and Agaoglu 2010). In the studies carried out (Marco et al 2000, Simsek et al 2014, there may be an increase in the animals during capture in masculine-based enzymes such as ALT, AST, CK and LDH depending on the physical stress that occurs in the animals and the levels of ALP, LDH, CK and glucose activities reduce with age, so these parameters are higher in the young than the old, besides the decrease in glucose level with age may be associated with weakening glucose regeneration in the liver. In our current study, in young animals in both genders, it has been detected that ALP activities in both groups are higher compared to the other groups, but the difference between them is not statistically significant (Table 4).…”

“…Due to giving important information to clinician physicians and researchers, the identification of normal values of many hematological and biochemical parameters, monitoring the health status and some illness processes of the animals are extremely important in terms of the evaluation of the diagnosis, treatment and prognosis of some diseases (Simsek et al 2014, Simsek et al 2015. That the studies about normal values of hematological and biochemical parameters of Van cats is less directed is to make a study in this direction.…”