Changes in the components of biliary and plasma lipids in selenium-deficient rats

Sakuma, Yasunobu; Sasaki, Junya; Futami, Aya; Yamasaki, Kosuke; Matsuoka, K.; Honda, Chikako; Endo, Kazutoyo; Tsukada, Masamichi

doi:10.1016/j.chemphyslip.2007.04.005

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…Lemley et al [38] reported that feed composition (a high cornstarch diet or high fiber diet) affected P4 clearance, and Sangsritavong et al [39] demonstrated that higher feed intake increased liver blood flow and steroid metabolism; however, neither feed intake nor the composition of the feed differed between the two treatment groups in this study. Steroid hormones are broken down in the liver and excreted via bile; however, Se status probably does not affect the composition (including the cholesterol) of bile [40]. We could not carry out a P4 infusion experiment to observe P4 clearance in this study, so it was unclear whether the increased plasma P4 concentration observed after Se supplementation was due to decreased catabolism of P4 in the liver.…”

Section: Discussionmentioning

confidence: 95%

Effects of selenium-rich yeast supplementation on the plasma progesterone levels of postpartum dairy cows

Kamada¹

2016

Asian-Australas J Anim Sci

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ObjectiveThe effects of the pre- and postpartum supplementation of cows with Se on their plasma P4 concentrations after calving were investigated.MethodsThirty-four Holstein cows were used to investigate the effects of dietary selenium supplementation on the postpartum recovery of the luteal function in cows. Selenium-rich yeast (containing 300 ppm selenium) was mixed with total mixed ration fed to 17 pregnant cows from 30 days before they were due to calve (10 g yeast daily) to 100 days after calving (20 g yeast daily). The control cows (n = 17) were fed the same amount of ordinary yeast. The cows’ plasma progesterone concentrations were determined every two days using an enzyme immunoassay after calving.ResultsFeed intake (total digestive nutrient, crude protein), milk production, body weight and the biochemical properties of blood plasma did not differ between the two groups; however, the plasma selenium concentrations of the supplemented animals were significantly greater than those of the controls at and after calving. The postpartum plasma progesterone concentrations of the selenium-yeast-supplemented group increased earlier than those of the control group. Moreover, during the estrus cycle after the 3rd ovulation or ovulation with estrus between 60 to 80 days after calving, the selenium-supplemented cows exhibited greater progesterone concentrations than the control cows.ConclusionSelenium supplementation promotes the postpartum progesterone production of cows.

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Section: Discussionmentioning

confidence: 95%

Effects of selenium-rich yeast supplementation on the plasma progesterone levels of postpartum dairy cows

Kamada¹

2016

Asian-Australas J Anim Sci

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“…Steroid hormones are dissimilated in liver and excreted via bile; however, Sakuma et al . () have reported that Se status does not affect the composition of bile. Further, if Se suppressed progesterone clearance, plasma progesterone concentration would increase throughout the whole experimental period; however, such an effect was not observed in this experiment.…”

Section: Discussionmentioning

confidence: 95%

Effects of selenium supplementation on plasma progesterone concentrations in pregnant heifers

Kamada

Nonaka

Takenouchi

et al. 2013

Animal Science Journal

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It is known that selenium (Se) has various functions in animals. Many investigations on the biochemical and physiological effects of Se have been previously reported; however, the detailed function of Se in reproduction is not yet clear. We proposed the possibility that Se plays a notable role in progesterone production. The aim of this study was to clarify the effects of Se supplementation on progesterone levels of pregnant Holstein heifers. Eight Holstein heifers (-Se) were fed basal diet (containing 0.022 ppm of Se) throughout the experiment. While a 0.3 ppm diet of Se (sodium selenite) was fed to another seven animals (+Se) with basal diet. Blood sampling was carried out every week. Plasma Se concentrations were higher in Se-supplemented cows compared with controls (-Se) (P < 0.01) throughout the experiment. Se supplementation increased plasma progesterone in the 29-39 weeks of pregnancy from 4.98 ± 0.64 to 6.86 ± 0.49 ng/mL on average (P < 0.05). The present findings suggest that Se contributes to maintaining the function of the corpus luteum and/or placenta in the latter period of pregnancy.

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Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency

et al. 2011

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The excretion of essential trace elements, namely, Se, Sr, As, Mn, Co, V, Fe, and Zn into the bile of Se-deficient (SeD) Wistar male rats was studied using the multitracer (MT) technique, and instrumental neutron activation analysis (INAA). Normal and Se-control (SeC) rat groups were used as reference groups to compare the effects of Se levels on the behaviors of the essential trace elements. The excretion (% dose) of Se, Sr, As, Mn, Co, and V increased with Se levels in the liver. The biliary excretion of Mn and As dramatically enhanced for SeC rats compared with SeD rats, while that of V accelerated a little for SeC rats. The radioactivity levels of (59)Fe and (65)Zn in the MT tracer solution were insufficient to measure their excretion into bile. The role of glutathione and bilirubin for biliary excretion of the metals was discussed in relation to Se levels in rat liver.

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Changes in the components of biliary and plasma lipids in selenium-deficient rats

Cited by 4 publications

References 32 publications

Effects of selenium-rich yeast supplementation on the plasma progesterone levels of postpartum dairy cows

Effects of selenium-rich yeast supplementation on the plasma progesterone levels of postpartum dairy cows

Effects of selenium supplementation on plasma progesterone concentrations in pregnant heifers

Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency

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