Changing epidemiologic patterns of typhus group rickettsiosis and scrub typhus in China, 1950-2022

Han, Ling; Zhang, Yunfei; Jin, Xiaojing; Ren, Hongyu; Teng, Zhongqiu; Sun, Zhaobin; Xu, Jianguo; Qin, Tian

doi:10.1016/j.ijid.2023.12.013

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence level of STG in Thailand demonstrated a notable increase between 2022 and 2023, with rates rising from 9.41:100,000 to 12.88:100,000 [ 2 ], accounting for a 36.9% increase in the incidence. This significant rise coincides with the current trends reported in multiple countries within the Tsutsugamushi Triangle, indicating a worrying surge in STG cases [ 15 , 16 , 17 , 18 ]. This trend, along with the urbanization of the disease and the identification of STG cases outside of the traditionally endemic regions [ 19 , 20 , 21 , 22 ], has heightened concerns regarding STG as a re-emerging threat.…”

Section: Introductionsupporting

confidence: 85%

Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand

Jitvaropas,

Sawaswong,

Poovorawan

et al. 2024

Viruses

View full text Add to dashboard Cite

The majority of cases of undifferentiated acute febrile illness (AFI) in the tropics have an undefined etiology. In Thailand, AFI accounts for two-thirds of illnesses reported to the Ministry of Public Health. To characterize the bacterial and viral causes of these AFIs, we conducted molecular pathogen screening and serological analyses in patients who sought treatment in Chum Phae Hospital, Khon Kaen province, during the period from 2015 to 2016. Through integrated approaches, we successfully identified the etiology in 25.5% of cases, with dengue virus infection being the most common cause, noted in 17% of the study population, followed by scrub typhus in 3.8% and rickettsioses in 6.8%. Further investigations targeting viruses in patients revealed the presence of Guadeloupe mosquito virus (GMV) in four patients without other pathogen co-infections. The characterization of four complete genome sequences of GMV amplified from AFI patients showed a 93–97% nucleotide sequence identity with GMV previously reported in mosquitoes. Nucleotide substitutions resulted in amino acid differences between GMV amplified from AFI patients and mosquitoes, observed in 37 positions. However, these changes had undergone purifying selection pressure and potentially had a minimal impact on protein function. Our study suggests that the GMV strains identified in the AFI patients are relatively similar to those previously reported in mosquitoes, highlighting their potential role associated with febrile illness.

show abstract

Section: Introductionsupporting

confidence: 85%

Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand

Jitvaropas,

Sawaswong,

Poovorawan

et al. 2024

Viruses

View full text Add to dashboard Cite

show abstract

Temporal shifts in 24 notifiable infectious diseases in China before and during the COVID-19 pandemic

Li,

Rui,

Song

et al. 2024

Nat Commun

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) pandemic, along with the implementation of public health and social measures (PHSMs), have markedly reshaped infectious disease transmission dynamics. We analysed the impact of PHSMs on 24 notifiable infectious diseases (NIDs) in the Chinese mainland, using time series models to forecast transmission trends without PHSMs or pandemic. Our findings revealed distinct seasonal patterns in NID incidence, with respiratory diseases showing the greatest response to PHSMs, while bloodborne and sexually transmitted diseases responded more moderately. 8 NIDs were identified as susceptible to PHSMs, including hand, foot, and mouth disease, dengue fever, rubella, scarlet fever, pertussis, mumps, malaria, and Japanese encephalitis. The termination of PHSMs did not cause NIDs resurgence immediately, except for pertussis, which experienced its highest peak in December 2023 since January 2008. Our findings highlight the varied impact of PHSMs on different NIDs and the importance of sustainable, long-term strategies, like vaccine development.

show abstract

Epidemiological Situation on Rickettsial Diseases and Q Fever in the Russian Federation over the Period of 2010–2023, Forecast for 2024

Shtrek,

Rudakov,

Shpynov

et al. 2024

Problemy Osobo Opasnykh Infektsii

View full text Add to dashboard Cite

The aim of the review is to forecast the incidence of rickettsial infections and Q fever in the Russian Federation for 2024 based on an analysis of the epidemiological situation in 2010–2023. The epidemic potential associated with these infections in Russia and other countries where there is an increased activity of foci with an expansion of the area of pathogen circulation has been assessed. An analysis of the incidence of epidemic typhus, Brill’s disease, Siberian tick-borne typhus (STT), Astrakhan spotted fever (ASF), Q fever, human granulocytic anaplasmosis, human monocytic ehrlichiosis in the Russian Federation in 2023 in comparison with long-term average values in 2010–2019 (COVID-19 pre-pandemic period) has been carried out. In 2023, the rates of registered incidence of rickettsial infections and Q fever in Russia as a whole decreased relative to the long-term average level of 2010–2019, and there is a significant downward trend in most regions. The exception is the Far Eastern Federal District, where the incidence rate of STT in 2023 increased by 1.5 times as compared to the period of 2010–2019, and the city of Sevastopol, where an increase in the incidence of Marseilles fever was detected. When assessing the intra-annual distribution of incidence in 2023, registration of STT in Russia was carried out from March to November inclusive, ASF – from May to October, and Q fever – from May to August.

show abstract

Changing epidemiologic patterns of typhus group rickettsiosis and scrub typhus in China, 1950-2022

Cited by 3 publications

References 20 publications

Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand

Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand

Temporal shifts in 24 notifiable infectious diseases in China before and during the COVID-19 pandemic

Epidemiological Situation on Rickettsial Diseases and Q Fever in the Russian Federation over the Period of 2010–2023, Forecast for 2024

Contact Info

Product

Resources

About