Chapter 10: Umbrella reviews

Aromataris, Edoardo; Fernandez, Ritin; Godfrey, Christina; Holly, Cheryl; Khalil, Hanan; Tungpunkom, Patraporn

doi:10.46658/jbimes-20-11

Cited by 107 publications

(149 citation statements)

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“…Researchers wishing to undertake an overview of reviews of healthcare interventions in 2020 still face a fragmented body of guidance documentation, but this should not overshadow the substantial developments in the science of overviews of reviews that have occurred over the past few years. In particular, both Cochrane [20] and the Joanna Briggs Institute [42] have released much needed updated handbook chapters that incorporate the most recent empirical evidence for producing overviews of reviews. Authors may use these stand-alone guidance documents to inform the planning of all stages of the overview of reviews.…”

Section: Discussionmentioning

confidence: 99%

Guidance for Overviews of Reviews Continues to Accumulate, But Important Challenges Remain: A Scoping Review

Gates

Guitard

et al. 2020

Preprint

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Background. Overviews of reviews (overviews) provide an invaluable resource for healthcare decision-making by combining large volumes of systematic review (SR) data into a single synthesis. The production of high-quality overviews hinges on the availability of practical evidence-based guidance for conduct and reporting.Objectives. Within the broad purpose of informing the development of a reporting guideline for overviews, we aimed to provide an up-to-date map of existing guidance related to the conduct of overviews, and to identify common challenges that authors face when undertaking overviews.Methods. We updated a scoping review published in 2016 using the search methods that had produced the highest yield: ongoing reference tracking (2014 to March 2020 in Pubmed, Scopus, and Google Scholar), hand-searching conference proceedings and websites, and contacting authors of published overviews. Using a qualitative meta-summary approach, one reviewer extracted, organized, and summarized the guidance and challenges presented within the included documents. A second reviewer verified the data and synthesis.Results. We located 28 new guidance documents, for a total of 77 documents produced by 34 research groups. The new guidance helps to resolve some earlier identified challenges in the production of overviews. Important developments include strengthened guidance on handling primary study overlap at the study selection and analysis stages. Despite marked progress, several areas continue to be hampered by inconsistent or lacking guidance. There is ongoing debate about whether, when, and how supplemental primary studies should be included in overviews. Guidance remains scant on how to extract and use appraisals of quality of the primary studies within the included SRs and how to adapt GRADE methodology to overviews. The challenges that overview authors face are often related to the above-described steps in the process where evidence-based guidance is lacking or conflicting.Conclusion. The rising popularity of overviews has been accompanied by a steady accumulation of new, and sometimes conflicting, guidance. While recent guidance has helped to address some of the challenges that overview authors face, areas of uncertainty remain. Practical tools supported by empirical evidence are needed to assist authors with the many methodological decision points that are encountered in the production of overviews.

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Section: Discussionmentioning

confidence: 99%

Guidance for Overviews of Reviews Continues to Accumulate, But Important Challenges Remain: A Scoping Review

Gates

Guitard

et al. 2020

Preprint

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“…In line with recommendations to improve transparency and reduce potential bias, the authors developed this protocol to outline the key objectives of this overview and what methodology will be employed 33 . This protocol was designed in accordance with the methodological framework provided by the Joanna Briggs Institute (JBI) Reviewer's Manual 36 , the Cochrane Handbook of Systematic Reviews of Interventions 37 and using the guidance of the relevant items of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) standardised reporting guidelines 38 .…”

Section: Protocolmentioning

confidence: 99%

“…The authors developed a comprehensive search strategy which has been peer reviewed by a dedicated Education and Health Sciences academic information specialist librarian using the Peer Review of Electronic Searches Model 40 . The aim of the search strategy is to locate all pertinent research, both published and unpublished systematic reviews, in accordance with best practice for conducting a search strategy for an overview 36 . A three-step search strategy will be utilised in this overview to ensure a comprehensive search of the literature 36 .…”

Section: Search Strategymentioning

confidence: 99%

“…The aim of the search strategy is to locate all pertinent research, both published and unpublished systematic reviews, in accordance with best practice for conducting a search strategy for an overview 36 . A three-step search strategy will be utilised in this overview to ensure a comprehensive search of the literature 36 . The authors conducted an initial search limited to EMBASE and PubMed databases to identify systematic reviews relevant to the overview research question.…”

Section: Search Strategymentioning

confidence: 99%

“…The authors conducted an initial search limited to EMBASE and PubMed databases to identify systematic reviews relevant to the overview research question. Following this, key words within the titles and abstract were identified and analysed and finally index terms for the systematic reviews were analysed in line with the recommendations for conducting a search strategy for an overview 36 . These steps guided the development of a search strategy including the identified keywords and index terms which will be adapted for each database for the second step of the search strategy 36 .…”

Section: Search Strategymentioning

confidence: 99%

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Effectiveness of interventions to reduce adverse outcomes among older adults following emergency department discharge: Protocol for an overview of systematic reviews

et al. 2020

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Background: Older adults are frequent users of Emergency departments (ED) and this trend will continue due to population ageing and the associated increase in healthcare needs. Older adults are vulnerable to adverse outcomes following ED discharge. A number of heterogeneous interventions have been developed and implemented to improve clinical outcomes among this cohort. A growing number of systematic reviews have synthesised evidence regarding ED interventions using varying methodologies. This overview aims to synthesise the totality of evidence in order to evaluate the effectiveness of interventions to reduce adverse outcomes in older adults discharged from the ED. Methods: To identify relevant reviews, the following databases will be searched: Cochrane Database of Systematic reviews, Joanna Briggs Institute Database of Systematic Reviews and Implementation Reports, Databases of Abstracts of Reviews of Effects, PubMed, MEDLINE, Epistemonikos, Ageline, Embase, PEDro, Scopus, CINAHL and the PROSPERO register. The search for grey literature will include Open Grey and Grey Literature Reports. Systematic reviews of randomised controlled trials will be analysed to assess the effect of ED interventions on clinical and process outcomes in older adults. Methodological quality of the reviews will be assessed using the Assessment of Multiple Systematic Reviews 2 tool. The review will be reported in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Summary of findings will include a hierarchical rank of interventions based on estimates of effects and the quality of evidence. Discussion: This overview is required given the number of systematic reviews published regarding the effectiveness of various ED interventions for older adults at risk of adverse outcomes following discharge from the ED. There is a need to examine the totality of evidence using rigorous analytic techniques to inform best care and potentially develop a hierarchy of treatment options. PROSPERO registration: CRD42020145315 (28/04/2020)

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Vital pulp therapy in carious pulp–exposed permanent teeth: an umbrella review

Leong

Yap

2021

Clin Oral Invest

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Chapter 10: Umbrella reviews

Cited by 107 publications

References 0 publications

Guidance for Overviews of Reviews Continues to Accumulate, But Important Challenges Remain: A Scoping Review

Guidance for Overviews of Reviews Continues to Accumulate, But Important Challenges Remain: A Scoping Review

Effectiveness of interventions to reduce adverse outcomes among older adults following emergency department discharge: Protocol for an overview of systematic reviews

Vital pulp therapy in carious pulp–exposed permanent teeth: an umbrella review

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