Chapter 2 Quinoline Alkaloids Related to Anthranilic Acid

Chapter 3 Chemical and Biological Aspects of Narcissus Alkaloids

“…The history of the Amaryllidaceae alkaloids, their structural elucidation, and their biological profiles, as well as their synthesis, have been summarized on several occasions (20,33,(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48) which, together with the regular publications in the journal Natural Product Reports (34,(49)(50)(51)(52)(53)(54)(55)(56)(57)(58)(59)(60)(61)(62)(63)(64)(65)(66), represent a valuable source of information.…”

2,3,3a,4,5,9b-Hexahydro-4-phenylfuro[3,2-c]quinoline

“…The pharmacological properties of quinoline alkaloids have been investigated to a limited degree, and thus evidence of antibacterial, antifungal and antiviral (HIV) activity has been observed (Grundon, 1998;Michael, 1998). Several quinoline alkaloids have also been found to show cytotoxic, phototoxic and mutagenic activity and to form cycloadducts with DNA (McCormick et al, 1996).…”

5-Benzyl-8-(E)-benzylidene-6,7,7a,10a-tetrahydro-5H-cis-cyclopenta[5,6]pyrano[3,3-c]quinolin-6-one

“…Pyranoquinolinones constitute a large group of naturally occurring biologically active compounds, such as¯indersine, veprisine, paraensidimerin and vepridimerine (Grundon, 1988;Chen et al, 1994). The quinolinones are a new class of antibiotics with therapeutic properties that are potentially attributable to their wide spectrum of antimicrobial activity (Fitten, 1992;McCarter et al, 1992).…”