Chapter 9. Assessing System Ontology in Biochemistry: Analysis of Students’ Problem Solving in Enzyme Kinetics

The identification of undergraduate chemistry students’ conceptual difficulties and common mistakes with basic concepts and problems in chemical kinetics provided the aim for this study, which involved 2nd-year/4th semester students who had passed the chemical kinetics component of a physical chemistry course. The study involved the analysis, evaluation and interpretation of students’ answers to the final examination in chemical kinetics. Three achievement groups, for the various topics, were identified: Group A, high achievement (mean ≈ 85%): (a) the steps in a chain-reaction mechanism, (b) integrated 1st- and 2nd-order rate laws; and (c) the Lindemann–Hinshelwood mechanism. Group B, intermediate achievement (mean ≈ 74%): (a) half-life, (b) instantaneous rate and the extent of reaction variable (ξ), (c) the Michaelis–Menten mechanism, and (d) theoretical rate law not asking for a final formula. Group C, low achievement (mean ≈ 54%): (a) experimental rate law and the reaction rate constant on the basis of an experimental-data table, (b) extracting the theoretical rate law, and (c) the Arrhenius equation. Students’ errors and misconceptions have also been identified. Successful students tended to respond well to straightforward questions on the theory of the subject, but had difficulties when solving problems. It is essential that teachers understand the potential of their students, especially possible misconceptions they may hold, and the teaching approaches that may contribute to overcoming the student difficulties. Problems in chemical kinetics can be very demanding both in terms of algebraic manipulations and conceptually. Teaching should focus on problem solving, with the emphasis on students themselves trying to solve the problems.

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Chapter 9. Assessing System Ontology in Biochemistry: Analysis of Students’ Problem Solving in Enzyme Kinetics

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Analysis of biochemistry students’ graphical reasoning using misconceptions constructivism and fine-grained constructivism: why assumptions about the nature and structure of knowledge matter for research and teaching

Analysis of biochemistry students’ graphical reasoning using misconceptions constructivism and fine-grained constructivism: why assumptions about the nature and structure of knowledge matter for research and teaching

Chemistry students’ conceptual difficulties and problem solving behavior in chemical kinetics, as a component of an introductory physical chemistry course

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