Background & Objective: Non-communicable diseases like systemic arterial hypertension (SAH) and dyslipidemia are poorly studied in terms of patient journey aspects. This semi-systematic review provides evidence synthesis for the management of SAH and dyslipidemia in Brazil and also discusses challenges faced by patients at the local level along with a suggested care approach by local experts.Methods: A semi-systematic review using both structured literature databases (Embase and Medline) and unstructured scientific records (WHO, IPD, MOH and Google) on hypertension and dyslipidemia in the English language from 2010–2019 was performed by reviewers. After two-level screening based on pre-defined criteria, patient journey touchpoints and prevalence information were extracted from the included articles. Data gaps were bridged through the insights of local experts.Conclusion: Limited patient education, regional disease distribution, and treatment allocation, along with limited resources for diagnosis and treatment are the key challenges. To improve overall patient journey considering critical touchpoints, timely and strict adoption of pharmacological treatment guidelines, campaigns for increased patient literacy about healthy diet and lifestyle modification, about the importance of self-reporting for early disease diagnosis, and benefits of treatment adherence are strongly recommended. Also, it is suggested to ensure the availability of skilled resources through continued education to render quality care to cardiovascular patients in Brazil.