Characterization and Biological Performance of Marine Sponge Collagen

Abstract

This study characterized the morphological aspects of marine collagenspongin (SPG) extract from marine sponges, as well as, evaluating its in vitro and in vivo biological performance. Aplysina fulva marine sponge was used for the SPG extraction. It was investigated the physicochemical and morphological properties of SPG by using scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and compared to PMMA and bovine collagen. Additionally, the SPG cytotoxicity and its influence on cell proliferation, through in vitro tests. Moreover, the in vivo biological response was investigated using HIGHLIGHTS  Marine collagensponginextract from specimens of the sponge Aplysina fulva. Spongin has physicochemical and morphological properties analogous to human collagen.