Pentaerythritol tetranitrate is considered a high explosive that has been widely studied for its chemical and
mechanical properties due to its nitrate ester group structure. Its applicability is intended from military purposes to
medicine and pharmacy. It is often a substitute for nitroglycerin and can be incorporated into polymeric matrices
that enhance its properties and make it safer to handle. In this work a synthesis of direct form elaborated according to
the reference material was presented, by the discontinuous nitration process, conducted in several steps starting from
Pentaerythritol (PE) with fuming nitric acid, having a very significant and expected yield according to data referenced
in previous studies. Fourier Transform Infrared Spectroscopy (FTIR-ATR), Thermogravimetric Analysis (TGA) and
Differential Scanning Calorimetry (DSC) analyzes confirm the chemical structure of the substance obtained and
the mass variation as a function of temperature, and typical information which can be derived from measurements
such as characteristic temperatures (melting, crystallization, reactions, glass transition) for characterization of high
energy materials. The explosive obtained by the new route proves to be effective and high yield.