Characterization of DNA absorption lines in the terahertz range

Duka, M. V.; Balbekin, Nikolay S.; Smolyanskaya, O. A.; Sobakinskaya, E. A.; Панин, А. Н.; Вакс, В. Л.

doi:10.1109/eiconrusnw.2015.7102290

Cited by 3 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The processes on a cellular level involved in the forming of responses are still largely unknown. It is known that also DNA absorbs vibration and can be altered by this [12]. In the clinical context, the application of vibration to osteosarcoma cells is one of the leading fields.…”

Section: Introductionmentioning

confidence: 99%

Experimental-Numerical Design and Evaluation of a Vibration Bioreactor Using Piezoelectric Patches

Valentín

Roehr

Presas

et al. 2019

Sensors

View full text Add to dashboard Cite

In this present study, we propose a method for exposing biological cells to mechanical vibration. The motive for our research was to design a bioreactor prototype in which in-depth in vitro studies about the influence of vibration on cells and their metabolism can be performed. The therapy of cancer or antibacterial measures are applications of interest. In addition, questions about the reaction of neurons to vibration are still largely unanswered. In our methodology, we used a piezoelectric patch (PZTp) for inducing mechanical vibration to the structure. To control the vibration amplitude, the structure could be excited at different frequency ranges, including resonance and non-resonance conditions. Experimental results show the vibration amplitudes expected for every frequency range tested, as well as the vibration pattern of those excitations. These are essential parameters to quantify the effect of vibration on cell behavior. Furthermore, a numerical model was validated with the experimental results presenting accurate results for the prediction of those parameters. With the calibrated numerical model, we will study in greater depth the effects of different vibration patterns for the abovementioned cell types.

show abstract

Section: Introductionmentioning

confidence: 99%

Experimental-Numerical Design and Evaluation of a Vibration Bioreactor Using Piezoelectric Patches

Valentín

Roehr

Presas

et al. 2019

Sensors

View full text Add to dashboard Cite

show abstract

Terahertz imaging technology for localization of cancer tumours: a technical review

Gezimati,

Singh

2023

Multimed Tools Appl

View full text Add to dashboard Cite

Currently, cancer is a large contributing factor in the increased mortality rates and at present the predictions are estimating an increased trend. The conventional medical cancer imaging modalities, for example X-Ray and Computed Tomography use ionizing radiation which is not tissue friendly for repeated assessments. The Terahertz (THz) cancer imaging offers novel opportunities for non-ionizing, non-invasive and early cancer detection, or diagnosis as well as improved cancer patient treatment follow-ups. In this review, a broad overview is given on the potential of THz radiation-based imaging and sensing as a technique for detection of various cancers cells. The THz radiation dynamics and interaction mechanisms with biological systems as well as parameter extraction and modelling for the observed THz image contrast are studied. The experimental studies on THz imaging and sensing are investigated with the goal approach to investigate the ex vivo, in vitro, and in vivo observations. The use of advanced analytic algorithms, specifically deep learning, is proposed for improved detection, discrimination of complex tissue with overlapping dielectric properties and development of clinical decision support systems. Research gaps in the THz imaging studies are identified based on recent trends, latest strategies suggested and the roadmap for future research direction provided.

show abstract

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

View full text Add to dashboard Cite

There is a keen interest in the exploration of new generation emitters and detectors due to advancements in innovation of new materials and device processing technologies which have opened up new frontiers in the Terahertz (THz) spectrum. Therefore, it is necessary to review the developments in THz technology for healthcare applications, their impact, implications and prospects for ongoing research and development. This paper provides a broad overview of the current status and prospects of application of THz imaging and sensing for the healthcare domain. We present current knowledge, identify existing challenges for wide scale clinical adoption of THz systems and prospective opinions to facilitate research and development towards optimized and miniaturized THz systems and biosensors that provide real operational convenience through emerging trends. Firstly, we provide an overview of the THz imaging and sensing techniques that exploit properties of THz generation and detection with emphasis on terahertz time domain spectroscopy (THz-TDS) and THz Metamaterials. The mechanisms of tissue image contrast and the application of THz imaging and sensing for biomedical applications in particular, the cancer detection application is reported. Secondly, an outlook toward the advancements in THz technology in the interface of healthcare 4.0 and its enabling technologies is explored for next generation smart and connected healthcare systems. Third, we identify the merits and existing challenges in THz cancer imaging and sensing and suggest prospective opinions to pave way to ongoing and future research. Further, we discuss the recent advances in THz imaging development and the contribution of near-field techniques based on plasmonic, and resonance based metasurfaces, waveguides etc. for breaking the diffraction limit towards development of THz systems that are convenient for point of care. We bring researchers a roadmap for future research scope.

show abstract

Characterization of DNA absorption lines in the terahertz range

Cited by 3 publications

References 5 publications

Experimental-Numerical Design and Evaluation of a Vibration Bioreactor Using Piezoelectric Patches

Experimental-Numerical Design and Evaluation of a Vibration Bioreactor Using Piezoelectric Patches

Terahertz imaging technology for localization of cancer tumours: a technical review

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Contact Info

Product

Resources

About