Characterization of materials eliciting foreign body reaction in stapled human gastrointestinal anastomoses

Lim, Chern Beverly Brenda; Goldin, Robert; Darzi, Ara; Hanna, G. B.

doi:10.1002/bjs.6071

Cited by 20 publications

(8 citation statements)

References 13 publications

(10 reference statements)

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“…13 In a porcine model, minimal fibrosis around the titanium staples was reported with only an occasional foreign-body giant-cell reaction. 14 However, Klein et al, 15 in the study in which a rat model was used, reported that there were no significant differences in fibrous tissue formation between titanium and absorbable polymeric surgical clips at any time.…”

Section: Discussionmentioning

confidence: 99%

Tissue Reaction to Absorbable Endoloop, Nonabsorbable Titanium Staples, and Polymer Hem-o-lok Clip After Laparoscopic Appendectomy

Delibegović

Iljazović

Katica

et al. 2011

JSLS

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Section: Discussionmentioning

confidence: 99%

Tissue Reaction to Absorbable Endoloop, Nonabsorbable Titanium Staples, and Polymer Hem-o-lok Clip After Laparoscopic Appendectomy

Delibegović

Iljazović

Katica

et al. 2011

JSLS

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“…15,16 Similar changes can also be seen in patients with metal allergies, such as nickel and/or titanium, who have abdominal surgery requiring use of stapling devices. 17,18 This actively inflamed gastric ulcer contains fibrin-rich granulation tissue with mixed inflammation, including numerous eosinophils (c). Sheets of eosinophils persist in the muscularis mucosae of a healing ulcer (d).…”

Section: Eosinophils As a Component Of Mixed Inflammationmentioning

confidence: 99%

Eosinophils in the GI tract: How many is too many and what do they mean?

Yantiss

2015

Modern Pathology

120

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Eosinophils are commonly detected in normal mucosal biopsies from all sites within the gastrointestinal tract where they are dispersed in the lamina propria and, to a lesser extent, in the epithelium. The distinction between the upper limit of normal and abnormally increased tissue eosinophils is not well defined. However, eosinophils that infiltrate the epithelium in more than occasional numbers, coalesce to form aggregates, or show extensive degranulation are always abnormal and raise a broad differential diagnosis. Although the differential diagnosis of purely eosinophilic inflammation is largely limited to hypersensitivity reactions and some infections, they are increased in several gastrointestinal conditions, including gastroesophageal reflux disease, autoimmune gastritis, infections, drug reactions, inflammatory bowel disease, radiation enteritis, and collagen vascular disease. These disorders feature eosinophils as one component of a mixed inflammatory infiltrate that can, in some instances, be prominent enough to cause diagnostic confusion. The purpose of this review is to discuss the normal distribution of eosinophils in the gastrointestinal tract and the differential diagnosis of inflammatory conditions that feature prominent eosinophilia.

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“…11 Lim et al confirmed the presence of foreign body reaction in stapled human GI anastomoses, the source of foreign materials eliciting this reaction being stapler cartridges. 12 Among the American and European surgeons who were trained in surgery at the end of the twentieth century, staplers were called “Russian Gun”. 13 …”

Section: Discussionmentioning

confidence: 99%

Stapled vs Conventional Hand-sewn Gastrointestinal Anastomosis during Infancy: A Prospective Comparative Study from Central India

Mitra¹,

Chandak²,

Kulkarni³

et al. 2020

Euroasian Journal of Hepato-Gastroenterology

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Background The creation of a joint between two bowel ends in newborns and infants is one of the core surgical procedures in pediatric surgery. For a proper and perfect gastrointestinal (GI) anastomosis, the factors to be considered are intraoperative duration, restoration of normal GI function, effective hemostasis, reduction of tissue damage, and prevention of postoperative mortality and morbidity. The safety and efficacy of stapled GI tract anastomosis in adults have been extensively documented; however, available literature on the same is limited for infants. Materials and methods Fifty-six patients were divided into two groups—stapled group and hand-sewn group. Patients operated on both emergency and elective basis were included in the study. Hand-sewn anastomosis was done by either end-to-end single-layer or double-layer anastomosis. Suture material used for the anastomosis was Vicryl 3-0 or Vicryl 4-0. Stapled anastomosis was done by 55 mm linear cutting GI stapler with side-to-side anastomosis. Results The present study included a total of 56 patients; there were 28 neonates and 28 infants; 37 of them were males. The most common clinical presentations were vomiting, abdominal distention, refusal to feed, and lethargy. The intraoperative duration in stapled GI anastomosis was less when compared to hand-sewn anastomosis, so was the return of bowel activity and consequently early initiation of feeds and shorter hospital stay. Conclusion The present study favors stapled over hand-sewn GI anastomosis in infancy in view of decreased intraoperative duration, reduced blood loss, early return of peristalsis, early initiation of feeds, and shorter duration of hospital stay. However, a small number of patients and lack of matching are the shortcomings of this study. How to cite this article Mitra AS, Chandak U, Kulkarni KK, et al. Stapled vs Conventional Hand-sewn Gastrointestinal Anastomosis during Infancy: A Prospective Comparative Study from Central India. Euroasian J Hepato-Gastroenterol 2020;10(1):11–15.

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Characterization of materials eliciting foreign body reaction in stapled human gastrointestinal anastomoses

Abstract: The presence of foreign body reaction was confirmed in stapled human gastrointestinal anastomoses. The source of refractile materials eliciting this reaction was the stapler cartridges.

Cited by 20 publications

References 13 publications

Tissue Reaction to Absorbable Endoloop, Nonabsorbable Titanium Staples, and Polymer Hem-o-lok Clip After Laparoscopic Appendectomy

Tissue Reaction to Absorbable Endoloop, Nonabsorbable Titanium Staples, and Polymer Hem-o-lok Clip After Laparoscopic Appendectomy

Eosinophils in the GI tract: How many is too many and what do they mean?

Stapled vs Conventional Hand-sewn Gastrointestinal Anastomosis during Infancy: A Prospective Comparative Study from Central India

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