Characterizing RNA modifications in the central nervous system and single cells by RNA sequencing and liquid chromatography–tandem mass spectrometry techniques

Patel, Arya; Clark, Kevin D.

doi:10.1007/s00216-023-04604-y

Anal Bioanal Chem

2023

DOI: 10.1007/s00216-023-04604-y

|View full text |Cite

Characterizing RNA modifications in the central nervous system and single cells by RNA sequencing and liquid chromatography–tandem mass spectrometry techniques

Arya Patel

Kevin D. Clark

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

RNA modification regulators as promising biomarkers in gynecological cancers

Qi,

Li,

Zhou

et al. 2024

Cell Biol Toxicol

View full text Add to dashboard Cite

This review explores the evolving landscape of gynecological oncology by focusing on emerging RNA modification signatures as promising biomarkers for assessing the risk and progression of ovarian, cervical, and uterine cancers. It provides a comprehensive overview of common RNA modifications, especially m6A, and their roles in cellular processes, emphasizing their implications in gynecological cancer development. The review meticulously examines specific m6A regulators including “writers”, “readers”, and “erasers” associated with three gynecological cancer types, discussing their involvement in initiation and progression. Methodologies for detecting RNA modifications are surveyed, highlighting advancements in high-throughput techniques with high sensitivity. A critical analysis of studies identifying m6A regulators as potential biomarkers is presented, addressing their diagnostic or prognostic significance. Mechanistic insights into RNA modification-mediated cancer progression are explored, shedding light on molecular pathways and potential therapeutic targets. Despite current challenges, the review discusses ongoing research efforts, future directions, and the transformative possibility of RNA modifications on early assessment and personalized therapy in gynecological oncology.

show abstract

RNA modification regulators as promising biomarkers in gynecological cancers

Qi,

Li,

Zhou

et al. 2024

Cell Biol Toxicol

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Characterizing RNA modifications in the central nervous system and single cells by RNA sequencing and liquid chromatography–tandem mass spectrometry techniques

Cited by 1 publication

References 48 publications

RNA modification regulators as promising biomarkers in gynecological cancers

RNA modification regulators as promising biomarkers in gynecological cancers

Contact Info

Product

Resources

About