Charged aerosol detection in pharmaceutical analysis

Sugar content in the sap of birches, hornbeams and maples in southeastern Poland

“…The linearity of the detector response was determined by the square correlation coefficients of the two calibration curves. Because of the well-known nonlinear Corona CAD response [18,19] it was necessary to make the calibration curve into two ranges (0.01-0.25 and 0.25-5.0 g L -1 respectively), generated by the injections of standard solutions of the three studied sugars: sucrose, glucose and fructose. The …”

Simultaneous determination of aspartame, acesulfame-K, saccharin, citric acid and sodium benzoate in various food products using HPLC–CAD–UV/DAD

“…Applications of the Corona CAD in the literature are varied and concern analysis of statins [21], xanthophylls [22], sugars [23], composition of structural carbohydrates [24], pharmaceutical formulations [25][26][27][28], amino acids [29] or saikosaponins [16]. Although an increasing number of papers about the CAD are being published in the literature, food additives analysis applications of the CAD are still rare [14].…”

Direct determination of amino acids by hydrophilic interaction liquid chromatography with charged aerosol detection

“…Charged aerosol detectors work similarly to evaporative light scattering detectors in that the column effluent is carried and aerosolized by a flow of nitrogen into a nebulizing chamber, where the low velocity large droplets are removed [45][46][47][48][49]. The remaining wide-range of droplet sizes are further dried into particles from single to hundreds of nanometers in size by passing through a drying tube.…”