Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases

Yanagawa, Toru; Yamaguchi, Akira; Harada, Hiroyuki; Yamagata, Kenji; Ishibashi, Naomi; Noguchi, Masayuki; Onizawa, Kojiro; Bukawa, Hiroki

doi:10.5402/2011/457567

Cited by 10 publications

(8 citation statements)

References 16 publications

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“…However, CG affecting female individuals, as in the present case, is an uncommon finding. 2,6,15 Regarding the age of diagnosis, most individuals were diagnosed in their 40s, 2 although studies reporting cases of CG affecting pediatric patients are available in the literature, 9,13,45 thus, as observed in our systematic review and elsewhere, 2,6 CG can affect individuals in all age groups (range: 5-84 years). The condition is more common in white-skinned individuals, 4,10,12,14,[20][21][22]24,26,37,41,44,45 and cases of CG in individuals with albinism have also been reported.…”

Section: Discussionmentioning

confidence: 51%

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Cheilitis glandularis: case report and systematic literature review

et al. 2022

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Cheilitis glandularis (CG) is a rare inflammatory disease of unknown etiology that affects the minor salivary glands predominantly in the lower lip. In this article, we report the case of an 18‐year‐old black woman who presented with a deep suppurative type of CG in both lips. In addition, we performed a systematic literature review in five databases (PubMed, Scopus, Web of Science, Ovid, and Embase) to identify CG case reports or case series. A total of 360 references were retrieved in the electronic databases. Thirty‐four articles met the inclusion criteria, and six were retrieved through manual search, totaling 40 articles included in the systematic review. Thirty‐nine (68.4%) cases occurred in male individuals and 18 (31.6%) in female individuals. The mean age of affected individuals was 40.9 years. Different clinical manifestations ranging from no symptoms to discomfort, pain, swelling, erythema, eversion of the lip, dilated ductal openings, ulcers, and crust have been reported. Among the included CG cases, 41 affected exclusively the lower lip (71.9%). In four cases, the CG only affected the upper lip (7.0%). In 12 cases, the lesion affected both the lower and upper lips (21.1%). Different treatment modalities were adopted in the management of CG. Although the surgical treatment was indicated (42.1%), the conservative treatment with topical medications, as in the present case, resulted in resolution in 21.0% of cases.

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Section: Discussionmentioning

confidence: 51%

“…Of the 40 studies included, eight were case series 8–15 and 32 were case reports, 3,4,16–45 totaling 57 cases analyzed in this systematic review.…”

Section: Resultsmentioning

confidence: 99%

Cheilitis glandularis: case report and systematic literature review

et al. 2022

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“…The deep suppurative type has also been variously referred to as myxadenitis labialis or cheilitis apostematosa, and the superficial suppurative type has been termed Baelz disease. [1][2][3][4][5][6][7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Cheilitis Glandularis of the Lower Lip

Patil¹

2017

IJDM

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Cheilitis glandularis is an uncommon disease most commonly affecting the lower lip caused by hyperplasia of minor salivary glands with the presence of inflammatory component. UV rays have been considered the primary cause for CG. It has categorized into 3 clinical types: simple, superficial suppurative, and deep suppurative. [1]. The lack of sufficient data makes the diagnosis and treatment of the disease cumbersome. Hereby we report a case of actinic cheilitis of the lower lip and discuss its diagnostic and therapeutic aspects.

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“…The main causes of CG are syphilis, bacterial infection, solar radiation, tobacco, poor oral hygiene and genetic factors. 71 , 72 Transformation of CG into SCC has been found by Nico et al 73 and Butt et al 74 Generally, a significant percentage of patients (18–36%) have been associated with the development of SCC of overlying epithelium of the lip. 75 …”

Section: Introductionmentioning

confidence: 93%