Chemical Analysis and Simulated Pyrolysis of Tobacco Heating System 2.2 Compared to Conventional Cigarettes

Abstract

To our knowledge, few independent studies of HNB products have been published. In this paper, a comprehensive list of chemical releases was tested systematically and compared to those from 3R4F. Although THS 2.2 generates lower levels of harmful constituents, the nicotine and tar levels were almost identical to 3R4F.The results should be discussed carefully in the future when assess the dual-use with other conventional cigarettes, nicotine dependence of HNB products, etc. This study also suggests that regulatory agencies should pay attention to the smoking regimes that are adopted to evaluate HNB tobacco products.

New ideas, old problems? Heated tobacco products – a systematic review

“…selected indoor air constituents were measured -the concentrations of respirable suspended particles, ultraviolet particulate matter, fluorescent particulate matter, solanesol, 3-ethenylpyridine, formaldehyde, acrolein, crotonaldehyde, acrylonitrile, benzene, 1,3-butadiene, isoprene, toluene, CO, NO and NO x after the use of THS2.2 under 3 environmental conditions were equivalent to the concentrations found in background indoor air -THS2.2 use resulted in increased acetaldehyde and nicotine concentrations in indoor air, but these concentrations were considerably lower than those found in conventional cigarettes The tobacco industry claims that the aerosol formed during the heating process has around 90-95% lower levels of toxicants than conventional cigarette smoke [13][14][15]23,24]. This was partially confirmed by independent studies [27,28]. Li et al reported that, compared to conventional cigarettes, IQOS delivered a > 90% lower concentration of harmful and potentially harmful constituents (HPHCs) except for carbonyls, ammonia, and N-nitrosoanabasine, where the levels were about 50-80% lower [27].…”

“…This was partially confirmed by independent studies [27,28]. Li et al reported that, compared to conventional cigarettes, IQOS delivered a > 90% lower concentration of harmful and potentially harmful constituents (HPHCs) except for carbonyls, ammonia, and N-nitrosoanabasine, where the levels were about 50-80% lower [27]. Farsalinos et al showed that IQOS use emitted substantially lower levels of carbonyls than a commercial cigarette but higher levels than an e-cigarette [28].…”

“…The tobacco industry claims that during HTP use, emissions of toxic chemicals are reduced due to the lower working temperature of the devices [13][14][15]23,24]. The results of independent studies suggest that toxic compounds are not completely removed from the HTP aerosol and these products are still not risk-free (Table 1) [7,19,[25][26][27][28][29][30][31][32][33][34][35]. Uchiyama et al compared the chemical composition of the aerosol from all 3 available heated tobacco products: IQOS with 4 different heat sticks, glo with 3 different heat sticks, and Ploom TECH with 3 different tobacco capsules, with smoke generated from 2 different reference cigarettes [7].…”

“…Water accounted for 75-85% of the total gaseous and particulate matter generated during IQOS and glo use, compared to 17-27% in the smoke from traditional cigarettes [7]. Heated tobacco products generated fewer chemical compounds compared to traditional cigarettes, except for water, propylene glycol, glycerol, and acetol, where the concentration in mainstream smoke was higher in heated tobacco than in traditional cigarettes [7,27]. Numerous studies, both independent and industry sponsored, have shown that the levels of nicotine contained in the aerosol released by HTPs (both regular and menthol versions) were 70-80% as those of conventional combustion cigarettes [15,27,29,33,36].…”

E-cigarettes – lesser evil?

“…W odniesieniu do e-papierosów typu heat-not-burn (podgrzewacze tytoniu) zaobserwowano znacznie niższą zawartość substancji toksycznych i kancerogennych wytwarzanych podczas ich użytkowania, w porównaniu z papierosami tradycyjnymi. Stwierdzono natomiast porównywalną zawartość substancji smolistych oraz nikotyny [30]. Uzyskane dane wskazują, że użycie urządzenia typu IQOS zmniejsza emisję niektórych szkodliwych związków, ale jednocześnie zwiększa ekspozycję na inne substancje, o nieznanej toksyczności [31].…”