Chemical Analysis of Renal Stones from 377 Belgian Patients by Using
Qualitative or Quantitative Methods

Fuss, Michel; Simon, Jonathan; Verbeelen, Dirk; Weiser, M; P, Van Landuyt; Elskens, I

doi:10.1159/000473919

Cited by 11 publications

(1 citation statement)

References 6 publications

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“…Two large-scale studies in the U. S. indicated that the percentage of stones containing uric acid as a primary constituent increased from 8.6% 3 to 16.5% 4 between 1962 and 1989, nearly doubling over a 27-year period. Comparable studies in other developed nations show that the prevalence of uric acid stones varies considerably, [5][6][7][8][9][10][11][12] ranging from a low of 4% in Sweden to a high of 39.5% in Israel. The pathogenic deposition of any crystalline species in vivo can be regarded, in essence, as a response to a solubility problem.…”

Section: Introductionmentioning

confidence: 99%

An in Situ Atomic Force Microscopy Study of Uric Acid Crystal Growth

2005

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Kidney stones are heterogeneous polycrystalline aggregates that can consist of several different building blocks. A significant number of human stones contain uric acid crystals as a crystalline component, though the molecular-level growth of this important biomaterial has not been previously well-characterized. In the present study, in situ atomic force microscopy (AFM) is used to investigate the real-time growth on the (100) surface of uric acid (UA) single crystals as a function of fundamental solution parameters. Layer-by-layer growth on UA (100) was found to be initiated at screw dislocation sites and to proceed via highly anisotropic rates which depend on the crystallographic direction. The smallest b-steps exhibited minimum heights corresponding to two molecular layers, while fast-moving c-steps more commonly showed monolayer heights. Growth kinetics measured under a range of flow rates, supersaturation levels, and pH values reveal linear trends in the growth kinetics, with faster growth attained in solutions with higher supersaturation and/or pH. The calculated kinetic parameters for UA growth derived from these experiments are in good agreement with the values reported for other crystal systems.

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Section: Introductionmentioning

confidence: 99%

An in Situ Atomic Force Microscopy Study of Uric Acid Crystal Growth

2005

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Natural Macromolecule‐Based Lubricative Catheter Coatings with Sustained Adaptive Antibacterial Property for Encrustation and Infection Prevention

Zhang,

Sun,

Song

et al. 2024

Adv Healthcare Materials

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Catheter‐associated urinary tract infection (CAUTI) are a global health burden. Moreover, the friction during urinary catheter placement also induces pain in patients. Therefore, there is a pressing need to develop effective antibacterial and lubricative coatings on the surface of urinary catheter. In this work, a facile volatilization film‐forming method is used to construct coatings on catheter surfaces. Xanthan gum (SR), which has good lubricative and antifouling properties, is oxidized to cross‐link with multi‐amino compounds, gentamicin (GS), and gelatin, to fabricate uniform coatings on silicone catheters (SR‐GXGs). The structures of SR‐GXGs are regulated by the components of the film formation solutions. The bacterial metabolism can produce an acidic micro‐environment that can regulate GS release to achieve on‐demand administration. SR‐GXG2 can eliminate 99.99% of common pathogenic bacteria and reduce the dynamic friction coefficient by 98.73%, and showed high stability in a 7‐day flowing experiment. In addition, the universality of this method is demonstrated on various kinds of matrices with different shapes, including commercial urethral catheters. In vivo, SR‐GXG2 can effectively avoid urinary tract injury and encrustation phenomenon because of its good anti‐infection, antifouling, and lubricative properties. This work provides a promising strategy for developing multifunctional antibacterial coatings on medical catheters.

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Epidemiology of Urolithiasis

Schneider¹

1985

Handbook of Urology

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Chemical Analysis of Renal Stones from 377 Belgian Patients by Using Qualitative or Quantitative Methods

Cited by 11 publications

References 6 publications

An in Situ Atomic Force Microscopy Study of Uric Acid Crystal Growth

An in Situ Atomic Force Microscopy Study of Uric Acid Crystal Growth

Natural Macromolecule‐Based Lubricative Catheter Coatings with Sustained Adaptive Antibacterial Property for Encrustation and Infection Prevention

Epidemiology of Urolithiasis

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