Chemical and Biochemical Reactors for Controlled Synthesis of Organic and Inorganic Compounds

Structure Screening of Oscillating Feedback Microreactors for the High-Throughput Synthesis of Zeolitic Imidazolate Framework-67 Nanoparticles with Controlled Size and Morphology

“…16−24 Compared with conventional batch processes, the approach of using microreactors can synthesize nanoparticles with narrow particle size distribution (PSD) and high reproducibility due to the precise control of experimental variables (e.g., concentration and temperature) in the small dimensions of microreactors. 25,26 However, most of the studies were focused on ordered microreactors (i.e., lamination flow 27 and segmented flow 28 microreactors). For the lamination flow microreactors, 29 the fluids usually flow side by side in a continuous mode, and mixing efficiency is relatively low due to the mass transfer being dominated by molecular diffusion.…”

“…However, these methods are usually carried out in batch mode, and the reproducibility of the products is not guaranteed, owing to the poor mixing efficiency of batch reactors. Recently, microreactors with high-efficient mass/heat transfer are used for the continuous synthesis of nanoparticles. − Compared with conventional batch processes, the approach of using microreactors can synthesize nanoparticles with narrow particle size distribution (PSD) and high reproducibility due to the precise control of experimental variables (e.g., concentration and temperature) in the small dimensions of microreactors. , However, most of the studies were focused on ordered microreactors (i.e., lamination flow and segmented flow microreactors). For the lamination flow microreactors, the fluids usually flow side by side in a continuous mode, and mixing efficiency is relatively low due to the mass transfer being dominated by molecular diffusion .…”