Chemical composition and antifungal activity of Salvia desoleana Atzei & Picci essential oil and its major components

Abstract

The antifungal activity of Salvia desoleana Atzei & Picci (Labiatae) essential oil and its three components was investigated against 17 micromycetes. Among the species tested were food-poisoning fungi and plant, animal and human pathogens. In order to determine minimum inhibitory concentrations (MICs) of the total essential oils and their components, mycelial growth and microdilution tests were used. The essential oil of S. desoleana and linalool possessed strong antifungal activity, 1,8-cineole showed only moderate antifungal potential, while linalyl acetate possessed a lower antifungal potential.

AFLP fingerprinting and essential oil profiling of cultivated and wild populations of Sardinian Salvia desoleana

“…The composition of the S. desoleana essential oil as determined here was consistent with those published elsewhere (Sokovic et al 2009;Peana et al 1999Peana et al , 1994.…”

“…The essential oil profiles of wild and cultivated populations of S. desoleana have not been thoroughly investigated before. Sokovic et al (2009) reported the presence of a small amount of sclareol (1.6 %) in a wild population sampled from the South of Sardinia in 1998, but no sclareol oxide. The lack of this compound in the Gergei population may be an effect of differences in the selection pressures prevailing in wild and cultivated sampling sites.…”

So Uncommon and so Singular, but Underexplored: An Updated Overview on Ethnobotanical Uses, Biological Properties and Phytoconstituents of Sardinian Endemic Plants

“…The essential oil of Salvia desoleana possesses antifungal properties against several mycromycetes. The activity probably derived from the synergistic action between different oil components, since the main components, such as linalyl acetate, 1,8-cineole and linalool, showed a slight antifungal activity [65]. Furthermore, even if it exerted a weak inhibition activity against S. aureus, S. epidermidis, E. coli and C. albicans, this inhibition increased progressively with contact time [66].…”

Natural Products from Plants and Fungi as Fungicides

“…A large number of plant compounds have been reported to have antifungal activity. Well known examples include; flavonoids (Ćirić et al, 2011;Karioti et al, 2011;Weidenbörner & Jha 1997), lactones (Djeddi et al, 2007;Janaćković et al, 2002;Skaltsa et al, 2000aSkaltsa et al, , 2000bVajs et al, 1999Vajs et al, , 2004, proteins (Giudici et al, 2000), sulfur compounds (Ilić et al, 2012), cyanogenic glycosides and glucosinolates (Osbourn, 1996) and essential oils (Daouk et al, 1995;Džamić et al, 2010;Garg & Siddiqui, 1992;Glamočlija et al, 2006aGlamočlija et al, , 2006bGlamočlija et al, , 2009Marinković et al, 2002;Mishra & Dubey, 1994;Müller-Riedau et al, 1995;Rančić et al, 2005;Shimoni et al, 1993;Soković, 2001Soković, , 2009aSoković, , 2009bSoković, , 2009cStojković et al, 2011bStojković et al, , 2011bThompson, 1989).…”

“…Linalyl acetate had the lowest antifungal potential. Values for MIC were lower with microdilution method (Soković et al, 2009a). The antifungal activity of Nepeta rtanjensis essential oil on mycelia growth has been determined by the diffusion method.…”