Chemical composition and antimicrobial activity of the essential oils of the Amazon Guatteriopsis species

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

“…It is the precursor of spathulenol, an oxygenated sesquiterpene that was one of the main constituents found in this oil (4.2%) ( Table 1) and could be considered as a chemotaxonomic marker of the Annonaceae family, since its presence is reported in its different genera (Costa et al, 2008). The other main sesquiterpene compounds were: γ-muurolene (7.9%), δ-cadinene (6.0%), (E)-caryophyllene (4.9%), spathulenol (4.2%), α-patchoulene (2.7%), sesquisabinene hydrate (2.5%) and α-humulene (2.4%) ( Table 1).…”

Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)

“…[19][20][21][22] Among these identified components, the oxygenated sesquiterpene spathulenol is considered as a chemotaxonomic marker of species of Annonaceae, because it has been identified in several species of this family belonging to the genera Annona, Artabotrys, Cleistopholis, Desmos, Duguetia, Fusae, Goniothalamus, Guatteria, Guatteriopsis, Hexalobus, Melodorum, Pachypodanthium, Piptostigma, Uvaria and Xylopia. 12,[19][20][21][22] (E)-caryophyllene is frequently found in the species of Annona, and could be considered together with caryophyllene oxide as chemotaxonomic markers for this genus. 12,[19][20][21][22] …”

Chemical constituents isolated from the bark of Guatteria blepharophylla (Annonaceae) and their antiproliferative and antimicrobial activities

“…Compounds 1-10 were identified by comparison of their spectroscopic data with those reported in the literature as caryophyllene oxide 19 (1), lichexanthone 20 (2), spathulenol 19 (3), a mixture of b-sitosterol 21 (4), and stigmasterol 21 (5), O-methylmoschatoline 22,23 (6), lysicamine 22,23 (7), nornuciferine 22 (8), liriodenine 6,23 (9), and isocoreximine 15 (10). Compounds 7-10 were recently found on the stem of this species, 15 while compounds 1-6, 11 and 12 were reported for the first time in this specie.…”

“…1 Plants of this family are known for their edible fruits and medicinal properties of many species. 2 Previous chemical and pharmacological investigations on some species of this family, including Guatteria, have indicated the presence of important bioactive compounds, exhibiting many pharmacological activities, such as, cytotoxicity against human tumor cell lines, [3][4][5] antimicrobial, 5,[6][7][8][9] and antiparasitic properties, particularly against Leishmania sp., 3,7,[10][11][12] Plasmodium falciparum 5,12,13 and Trypanosoma sp. 3,12,14 Despite the importance of annonaceous members in folk medicine, the number of species that have been chemically investigated is still very small.…”

“…15 Previous phytochemical studies on this species described the isolation and identification of essential oils and isoquinoline alkaloids. 8,15,16 In continuation of our research on bioactive compounds from Amazonian annonaceous plants, we report herein the phytochemical study of the bark of G. blepharophylla and the evaluation of antiproliferative and antimicrobial properties of the main isolated compounds. …”