Chemical Composition and Antimicrobial Activity of Essential Oil of <i>Cupressus atlantica</i>

Arjouni, My Youssef; Bahri, Fouad; Romane, Abderrahmane; Fels, My Ahmed El Alaoui El

doi:10.1177/1934578x1100601028

Cited by 7 publications

(7 citation statements)

References 8 publications

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“…73% contraction of the C. atlantica range over a period of 36 years. This significant reduction in a relatively short time is a consequence of the strong anthropogenic pressure, mostly illegal logging and branch cutting (El Wahidi 2004;Arjouni et al 2011). In 1998, Griffiths (1998) estimated that 84% of cypress trees were damaged by humans in several stands in the Oued N'Fiss, which was also confirmed in a more recent survey (Sękiewicz et al 2014) (Fig.…”

Section: Species Distribution Patternsmentioning

confidence: 78%

High genetic diversity and low future habitat suitability: will Cupressus atlantica, endemic to the High Atlas, survive under climate change?

et al. 2020

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Cupressus atlantica is a narrow endemic species of semi-arid and sub-humid habitats in the western High Atlas, Morocco. We explored the possible dynamics of the species’ range under climatic changes using species distribution modelling (SDM) to identify populations vulnerable to range changes. Additionally, we investigated the spatial genetic structure (SGS), the effective population size and genetic connectivity in natural populations, which may provide important data on demo-genetic processes and support the conservation management of this critically endangered species. The SDM results showed that the current species range constitutes only 49% of the potential distribution. Under the most pessimistic scenarios (RCP6.0 and RCP8.5), a significant reduction in the species range was predicted. However, the projection based on RPC4.5 revealed possible extensions of the habitats suitable for C. atlantica. Potentially, these areas could serve as new habitats that could be used with the assisted migration approach aiming to mitigate the current fragmentation. In terms of the SGS, significant and positive aggregation of relatives was detected up to ca. 100 m. In comparison to other fragmented and endemic species, the detected SGS was weak (Sp = 0.0112). The estimated level of recent gene flow was considerable, which likely prevented a strong SGS and allowed diversity to accumulate (HE = 0.894). The most alarming results concern the effective population size, which was very low in the studied populations (< 53), suggesting a possible increase in inbreeding and loss of diversity in the near future. More effective conservation actions integrating in situ and ex situ measures should be undertaken to prevent extirpation of the species.

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Section: Species Distribution Patternsmentioning

confidence: 78%

High genetic diversity and low future habitat suitability: will Cupressus atlantica, endemic to the High Atlas, survive under climate change?

et al. 2020

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“…α-Phellandrene (α-PHE), a cyclic monoterpene, is a natural compound that can occur in two enantiomeric forms: (−)-α-PHE and (+)-α-PHE. α-PHE is present in the volatile oil of several plants and in varied concentrations [ 146 ], such as Anethum graveolens (32%) [ 147 ], Solanum erianthum (17.5%) [ 148 ], Schinus terebinthifolius (15.7%) [ 149 ], Curcuma zedoaria (14.9%) [ 150 ], Thymus kotschyanus (10.8%) [ 151 ] and Cupressus atlantica (5.5%) [ 152 ]. Furthermore, this constituent has been associated with the antinociceptive and anti-inflammatory properties of some species, including Matricaria chamomilla [ 153 ], Schinus polygamus [ 154 ] and Zingiber officinale [ 155 ].…”

Section: Resultsmentioning

confidence: 99%

Analgesic-Like Activity of Essential Oil Constituents: An Update

Sá

Lima

Nóbrega

et al. 2017

IJMS

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The constituents of essential oils are widely found in foods and aromatic plants giving characteristic odor and flavor. However, pharmacological studies evidence its therapeutic potential for the treatment of several diseases and promising use as compounds with analgesic-like action. Considering that pain affects a significant part of the world population and the need for the development of new analgesics, this review reports on the current studies of essential oils’ chemical constituents with analgesic-like activity, including a description of their mechanisms of action and chemical aspects.

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“…Anti-microbial activity [45] 3-Methyl-2-furoic acid Anti-fungal and anti-tumor activity [46] 2,4-Octadienoic acid, 7-hydroxy-6-methyl Analgesic and anti-inflammatory activity [47] Diethyl mercaptal of d-mannose Antibacterial and anti-fungal activity [48] dl-Allo-cystathionine Analgesic, anti-inflammatory, antifungal, antibacterial activity [49] Phloroglucinol Antioxidant, antineoplastic, anti-inflammatory, antimicrobial, antifungal activity [50,51] Acetoacetic acid, 1,3-dithio-, S-ethyl ester Analgesic, antipyretic, antimalarial and antibiotic effect [52,53] β-D-Glucopyranose, 1,6-anhydro-Anti-bacterial and antioxidant effect [54,55] D-Allose Antioxidant, antibacterial and antiviral activity [56,57] Germacrene D Neurological activity, cytotoxicity and antimicrobial activity [58,59] Cis-muurola-3,5-diene Antimicrobial activity [60] β-copaene Cytotoxic and antioxidant effect [61,62] Decanal Antioxidant [63] Dodecanoic acid, 3-hydroxy-Antibacterial, antitumor and antioxidant effect [64] Butanoic acid, octyl ester Effect on CNS, antioxidant, analgesic and anti-inflammatory activity [65,66] Quinic acid Antibacterial, antiviaral, antioxidant and hepatoprotective activity [67][68][69] 1-Heptanol, 2,4-dimethyl-, (R,R)-(+)-Antifungal activity [70] d-Mannitol, 1-decylsulfonyl-Anti-diabetic, anti-microbial activity [71,72] d-Mannitol, 1-thiohexyl-1-deoxy-Anti-microbial activity [73] 4-Diazodamantanone Antimicrobial, anti-inflammatory and antiacetylcholinesterase activities [74,75] 3-Nonyn-2-ol Anti-inflammatory, anti-septic, anti-tumor activity [76,77] Chlorozotocin Anti-tumor, reduction in bone marrow toxicity…”

Section: Compound Name Biological Activity References 124 Benzenetriolmentioning

confidence: 99%

GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents

et al. 2020

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Chukrasia velutina is a local medicinal plant commonly known as chikrassy in Bangladesh, India, China, and other South Asian countries. The leaves, bark, and seeds are vastly used as herbal medicine for fever and diarrhea, and its leaves essential oils are used for antimicrobial purposes. In this study, we discuss the neuropsychiatric properties of C. velutina leaves through several animal models, quantitative and qualitative phytochemical analysis, and computational approaches. Neuropsychiatric effects were performed in rodents on the methanolic extract of C. velutina leaves (MECVL). Antidepressant, anxiolytic, and sedative effects experimented through these rodent models were used such as the force swimming test (FST), tail suspension test (TST), hole board test (HBT), elevated plus maze test (EPMT), light/dark box test (LDBT), open field test (OFT), and hole cross test (HCT). In these rodent models, 200 and 400 mg/kg doses were used which exhibited a significant result in the force swimming and tail suspension test (p < 0.001) for the antidepressant effect. In the anxiolytic study, the results were significant in the hole board, elevated plus maze, and light/dark box test (p < 0.001) for doses of 200 and 400 mg/kg. The result was also significant in the open field and hole cross test (p < 0.001) for sedative action in the sake of similar doses. Moreover, qualitative and quantitative studies were also performed through phytochemical screening and GC-MS analysis, and fifty-seven phytochemical compounds were found. These compounds were analyzed for pharmacokinetics properties using the SwissADME tool and from them, thirty-five compounds were considered for the molecular docking analysis. These phytoconstituents were docking against the human serotonin receptor, potassium channel receptor, and crystal structure of human beta-receptor, where eight of the compounds showed a good binding affinity towards the respective receptors considered to the reference standard drugs. After all of these analyses, it can be said that the secondary metabolite of C. velutina leaves (MECVL) could be a good source for inhibiting the neuropsychiatric disorders which were found on animal models as well as in computational studies.

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Chemical Composition and Antimicrobial Activity of Essential Oil of Cupressus atlantica

Cited by 7 publications

References 8 publications

High genetic diversity and low future habitat suitability: will Cupressus atlantica, endemic to the High Atlas, survive under climate change?

High genetic diversity and low future habitat suitability: will Cupressus atlantica, endemic to the High Atlas, survive under climate change?

Analgesic-Like Activity of Essential Oil Constituents: An Update

GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents

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