Chemical Composition and Antimicrobial Properties of Piper ovatum Vahl

Silva, Daniel Rodrigues; Endo, Eliana Harue; Filho, Benedito Prado Dias; Nakamura, Celso Vataru; Svidzinski, Terezinha Inez Estivaleti; Souza, Amanda de; Young, Maria Cláudia M.; Ueda-Nakamura, Tânia; Cortez, Diógenes Aparı́cio Garcia

doi:10.3390/molecules14031171

Cited by 39 publications

(24 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Antifungal tests proved the inhibition of C. tropicalis. [227] Dalleau et al compared the anti-biofilm activity of molecules which are often prevalent in EOs. The effect of thymol, carvacrol, a-terpinene, 1,8-cineole, menthol, citral, linalool, eugenol, farnesol and geraniol was measured by 24-h treatment of Candida biofilms which had been developed for 1-5days.…”

Section: Candidamentioning

confidence: 99%

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

Lang

Buchbauer

2011

Flavour & Fragrance J

344

209

View full text Add to dashboard Cite

The antimicrobial activity of essential oils is discussed in this review taking in account studies which were published in the period of time from 2008 until September 2010. Furthermore, the most important methods to examine the antimicrobial efficiency of essential oils are presented. The studies are divided into the following two groups, namely antibacterial and antifungal active agents depending on the activity of the applied essential oil against the test microorganisms. Various interesting possible applications are revealed such as the use of essential oils instead of synthetic drugs to circumvent the increasing resistance of some pathogens. Moreover, they could not only be used for the therapy of infectious illnesses, but also as preservatives in the food industry. A further possibility is, among others, the application of essential oils in skin products in order to treat or avoid dermal infections. Additionally, the prevalent constituents of the individual antimicrobial active essential oils are elaborated.

show abstract

Section: Candidamentioning

confidence: 99%

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

Lang

Buchbauer

2011

Flavour & Fragrance J

344

209

View full text Add to dashboard Cite

show abstract

“…Piper species are used in traditional remedies and folklore medicine all over the world for their antioxidant [3–5], antimicrobial [6–8], anti-inflammatory [9–12] and antifungal [13–15] activities.…”

Section: Introductionmentioning

confidence: 99%

Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume

Salleh

Ahmad

Khong

et al. 2011

IJMS

View full text Add to dashboard Cite

Chemical composition, antioxidant and antimicrobial activities of the fresh leaves and stems oils of Piper caninum were investigated. A total of forty eight constituents were identified in the leaves (77.9%) and stems (87.0%) oil which were characterized by high proportions of phenylpropanoid, safrole with 17.1% for leaves and 25.5% for stems oil. Antioxidant activities were evaluated by using β-carotene/linoleic acid bleaching, DPPH radical scavenging and total phenolic content. Stems oil showed the highest inhibitory activity towards lipid peroxidation (114.9 ± 0.9%), compared to BHT (95.5 ± 0.5%), while leaves oil showed significant total phenolic content (27.4 ± 0.5 mg GA/g) equivalent to gallic acid. However, the essential oils showed weak activity towards DPPH free-radical scavenging. Evaluation of antimicrobial activity revealed that both oils exhibited strong activity against all bacteria strains with MIC values in the range 62.5 to 250 μg/mL, but weak activity against fungal strains. These findings suggest that the essential oils can be used as antioxidant and antimicrobial agents for therapeutic, nutraceutical industries and food manufactures.

show abstract

“…[19] To develop a HPLC method for the analysis of amides in P. ovatum extracts, several parameters were optimized to select the proper conditions. A gradient was chosen that allowed good separation of amides within a short analysis time.…”

Section: Resultsmentioning

confidence: 99%

“…[161718] The amides piperovatine and piperlonguminine from P. ovatum leaves, and showed MIC values of 15.6 and 31.2μg/mL to B. subtilis and 3.9μg/mL to C. tropicalis , and low toxic effects to Vero cells and macrophages and the essential oil was active against C. tropicalis . [19]…”

Section: Introductionmentioning

confidence: 99%

Analysis of amide compounds in different parts of Piper ovatum Vahl by high-performance liquid chromatographic

et al. 2013

View full text Add to dashboard Cite

Background:Piper ovatum (Piperaceae) has been used in traditional medicine for the treatment of inflammations and as an analgesic. Previous studies have showed important biological activities of the extracts and amides from P. ovatum leaves.Objective:In this study, a high-performance liquid chromatographic (HPLC) method was developed and validated for quantitative determination of the amides in different parts of Piper ovatum.Materials and Methods:The analysis was carried out on a Metasil ODS column (150 × 4.6 mm, 5μm) at room temperature. HPLC conditions were as follows: acetonitrile (A), and water (B), 1.0% acetic acid. The gradient elution used was 0–30 min, 0-60% A; 30–40 min, 60% A. Flow rate used was 1.0mL/min, and detection at 280nm.Results:The validation using piperlonguminine, as the standard, demonstrated that the method shows linearity (linear correlation coefficient = 0.998), precision (relative standard deviation <5%) and accuracy (mean recovery = 103.78%) in the concentration range 31.25 – 500μg/mL. The limit of detection and quantification were 1.21 and 4.03μg/mL, respectively. This method allowed the identification and quantification of piperlonguminine and piperovatine in the hydroethanolic extracts of P. ovatum obtained from the leaves, stems and roots. All the extracts showed the same chromatographic profile. The leaves and roots contained the highest concentrations of piperlonguminine and the stems and leaves showed the most concentrations of piperovatine.Conclusion:This HPLC method is suitable for routine quantitative analysis of amides in extracts of Piper ovatum and phytopharmaceuticals containing this herb.

show abstract

Chemical Composition and Antimicrobial Properties of Piper ovatum Vahl

Cited by 39 publications

References 16 publications

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review.

Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume

Analysis of amide compounds in different parts of Piper ovatum Vahl by high-performance liquid chromatographic

Contact Info

Product

Resources

About