“…In a recent work, Ben Attia et al (2018) compared the chemical compositions of C. coccineum plants from Sardinia and Tunisia, describing a differential chemical profile, possibly due to the climatic conditions (more arid in the Tunisian desert, and temperate in the Mediterranean basin). The phenolics, in fact, were differently distributed among solvents at various polarities [33]. Additionally, these authors used 1 H-NMR to identify several amino acids (including proline, glutamine, valine, threonine, alanine, and asparagine) and mono-, bi-, and tricarboxylic organic acids (i.e., acetate, formate, and several common intermediates of biochemical pathways such as citrate, fumarate, malate, malonate, and succinate) in Sardinian and Tunisian samples.…”