Chemical Composition and Free Radical Scavenging Activity of Essential Oils and Extracts of Algerian<i>Cardaria draba</i>(L.) Desv.

Younes, Kawther; Merghache, Salima; Djabou, Nassim; Selles, Chaouki; Muselli, Alain; Tabti, Boufeldja; Costa, Jean

doi:10.1080/0972060x.2014.974077

Cited by 9 publications

(5 citation statements)

References 12 publications

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“…The DPPH radical scavenging activity in the extract obtained from the leaf parts was found to be 86.85% and 92.48%, respectively. In the ethanolic extract obtained by using the stem parts, this value was found to be 90.61% by Younes et al, (2015). Eruygur et al, (2022) who examined the methanolic, ethanolic and aqueous extracts of the flower, stem, root and leaf parts of Lepidium draba, determined the DPPH radical scavenging activities as IC 50 were found 1.57, 2.02 and 1.27 mg mL -1 for the flower, 6.51, 9.04 and 11.14 mg mL -1 for stem, 8.30, 6.14 and 2.39 mg mL -1 for the root portion and 3.11, 3.12 and 5.27 mg mL -1 for the leaves respectively.…”

Section: Resultsmentioning

confidence: 95%

“…Dichloromethane, water and ethyl alcohol were used as solvents. Total phenolic content was found to be 19 620, 57 790 and 41 820 μg GAE g -1 herb for the leaf part, and 12 230, 30 410 and 19 310 μg GAE/g herb for the stem part, respectively (Younes et al, 2015). In the study by Eruygur et al, different parts of Lepidium draba (flower, stem, root and leaf) were used as ethanol, methanol and aqueous solvent.…”

Section: Resultsmentioning

confidence: 99%

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Antioxidant Properties, Total Phenolic Content and LC-MS/MS Analysis of Mentha Pulegium, Lepidium Draba and Centaurea Solstitialis

Necip

Durgun

2022

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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The Mentha pulegium, Lepidiıum draba and Centaurea solstitialis have traditionally been used in different cultures for the treatment of various diseases. We investigated the total phenolic content analysis, chemical compositions and antioxidant activities of different solvent extracts such as acetone, methanol and n-hexane obtained from the aerial parts of Mentha pulegium, Lepidiıum draba and Centaurea. The amount of total phenolic substance was determined as gallic acid equivalent determine. Also, the LC-MS/MS technique was used to determine the phenolic profiles of each extract. Finally, antioxidant activities of three extracts were determined by DPPH and ABTS methods. The highest total phenolic content for acetone, n-hexane and methanol extracts was found as 99 507, 46 305, and 18 227 μg GAE mL-1 in Centaurea solstitialis plant, respectively. While the major component rosmarinic acid amount in the acetone extract of Mentha pulegium was 128 195 μg analyte g-1 extract, this amount was determined as 780 383 μg analyte g-1 extract in the methanolic extract. The highest DPPH radical scavenging activity was found in the acetone and methanolic extracts of Mentha pulegium as 77% and 79%, respectively. ABTS radical scavenging activity was also found to be 98% and 94% for Mentha pulegium in acetone and methanol extracts, respectively. The antioxidant capacity of the extracts is related to the total amount of phenolic substances.

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Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Antioxidant Properties, Total Phenolic Content and LC-MS/MS Analysis of Mentha Pulegium, Lepidium Draba and Centaurea Solstitialis

Necip

Durgun

2022

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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“…Recent studies of various Brassica plants have revealed hoary cress characterized by allelopathic [77,78] and antioxidant properties [79,80]. This plant contains, in addition to GRN, only a small number of other GLSs [81][82][83][84], which makes it a preferred source of GRN.…”

Section: Discussionmentioning

confidence: 99%

The Antimicrobial Effects of Myrosinase Hydrolysis Products Derived from Glucosinolates Isolated from Lepidium draba

Polozsányi,

Galádová,

Kaliňák

et al. 2024

Plants

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Lepidium draba (hoary cress) is a perennial plant belonging to the Brassicaceae family that produces two dominant glucosinolates (GLSs): glucoraphanin (GRN) and sinalbin (SBN). They represent the stored form, which is converted upon the myrosinase (Myr) hydrolysis activity to active compounds, mainly isothiocyanates (ITCs) such as sulforaphane (SFN) or p-hydroxybenzyl isothiocyanate (pHBITC). Research on ITCs that have proven anticancer, antimicrobial, and chemoprotective properties is usually conducted with pure commercially available compounds. However, these are chemically reactive, making it difficult to use them directly for preventive purposes in dietary supplements. Efforts are currently being made to prepare dietary supplements enriched with GLS and/or Myr. In this study, we report a simple but efficient chromatographic procedure for the isolation and purification of GLSs from MeOH extract from hoary cress based on a combination of ion exchange and gel permeation chromatography on DEAE-Sephadex A-25 and Sephadex LH-20. To obtain the Myr required for efficient hydrolysis of GLSs into antibacterial ITCs, we developed a rapid method for its extraction from the seeds of Lepidium sativum (garden cress). The yields of GLSs were 22.9 ± 1.2 mg GRN (purity 96%) and 10.4 ± 1.1 mg SBN (purity 92%) from 1 g of dry plant material. Both purified GLSs were used as substrates for the Myr. Analysis of the composition of hydrolysis products (HPs) revealed differences in their hydrolysis rates and in the degree of conversion from GLSs to individual ITCs catalyzed by Myr. When GRNs were cleaved, SFNs were formed in an equimolar ratio, but the formation of pHBITCs was only half that of cleaved SBNs. The decrease in pHBITC content is due to its instability compared to SFN. While SFN is stable in aqueous media during the measurement, pHBITC undergoes non-enzymatic hydrolysis to p-hydroxybenzyl alcohol and thiocyanate ions. Testing of the antimicrobial effects of the HPs formed from GRN by Myr under premix or in situ conditions showed inhibition of the growth of model prokaryotic and eukaryotic microorganisms. This observation could serve as the jumping-off point for the design of a two-component mixture, based on purified GLSs and Myr that is, usable in food or the pharmaceutical industry in the future.

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“…This is in agreement with those observed by other researchers on different medical plants (Katalinic et al, 2006; Moussa et al, 2011; Nikolova, 2011). Younes et al (2015) documented that leave ethanolic extract of Algerian Cardaria draba (L) has considerable DPPH antioxidant activity. Studies have shown that polyphenols with plants origin are among the important antioxidants (Houghton et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

Renoprotective and hepatoprotective activity of Lepidium draba L. extracts on oxymetholone‐induced oxidative stress in rat

Feng

Gao

Yang

et al. 2022

Journal of Food Biochemistry

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Chemical Composition and Free Radical Scavenging Activity of Essential Oils and Extracts of AlgerianCardaria draba(L.) Desv.

Cited by 9 publications

References 12 publications

Antioxidant Properties, Total Phenolic Content and LC-MS/MS Analysis of Mentha Pulegium, Lepidium Draba and Centaurea Solstitialis

Antioxidant Properties, Total Phenolic Content and LC-MS/MS Analysis of Mentha Pulegium, Lepidium Draba and Centaurea Solstitialis

The Antimicrobial Effects of Myrosinase Hydrolysis Products Derived from Glucosinolates Isolated from Lepidium draba

Renoprotective and hepatoprotective activity of Lepidium draba L. extracts on oxymetholone‐induced oxidative stress in rat

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