Chemical composition, antimicrobial activity against Staphylococcus aureus and a pro-apoptotic effect in SGC-7901 of the essential oil from Toona sinensis (A. Juss.) Roem. leaves

Abstract

TSL-EO possessed antibacterial activity against Staphylococcus aureus and significant cytotoxicity against cancer cells and particularly prominent pro-apoptotic activity in SGC7901 cells. These bioactivities were probably due to the high content of sesquiterpenes. Our results suggested that TSL-EO possessed potential health benefits and could serve as a promising natural food addictive.

KERAGAMAN MORFO-FISIOLOGI BENIH SUREN (Toona sinensis) DARI BERBAGAI TEMPAT TUMBUH DI SUMATERA DAN JAWA

“…M. Roem, sinonim Cedrela sinensis) merupakan jenis pohon yang memiliki banyak manfaat. Kayunya bernilai ekonomi tinggi sebagai bahan venir, kayu lapis, kontruksi, furnitur, kerajian, sedangkan bagian tanaman lainnya seperti daun, biji dapat digunakan untuk bahan obat-obatan dan kosmetik (Chen, 2012;Wu et al, 2014) dan insektisida tradisional (Asmaliyah & Ismail, 2013;Darwiati, 2009). Jenis ini merupakan jenis asli India dan Nepal yang diintroduksi ke arah timur melewati China, Burma, Thailand, Malaysia hingga ke Jawa (Edmonds & Staniforth, 1998).…”

Antioxidant and Anti-proliferative Activities of Flavonoids from <i>Bidens pilosa</i> L var <i>radiata</i> Sch Bip

“…Furthermore, uncontrolled cell proliferation would eventually result in a net increase in the number of cancer cells, which is strongly associated with the development and progression of cancer [3]. In this respect, removing ROS/RNS generated in excess and restraining cancer cell proliferation are considered an effective means to fight cancer [4]. Recently, a great concern has been focused on searching for potential anticancer agents of natural origin [5].…”

Anticancer Activity of Essential Oils: Targeting of Protein Networks in Cancer Cells

“…There was notably enhanced expression of caspase-3 and Bax in gastric cancer cell line SGC-7901 upon treatment with Essential oils from Toona sinensis. Detailed chemical analysis of Essential oil indicated that there was a higher percentage of sesquiterpenes including β-caryophyllene, β-eudesmene, copaene and caryophyllene as evidenced by GC/MS (Wu et al, 2014). Essential oil from Lavandula angustifolia was effective against MCF-7 and HeLa cell lines.…”