β-PdBi2 has attracted much attention for its prospective ability to possess simultaneously topological surface and superconducting states due to its unprecedented spin-orbit interaction (SOC). Whereas most works have focused solely on investigating its topological surface states, the coupling between spin and charge degrees of freedom in this class of quantum material remains unexplored. Here we first report a study of spin-to-charge conversion in a β-PdBi2 ultrathin film grown by molecular beam epitaxy, utilizing a spin pumping technique to perform inverse spin Hall effect measurements. We find that the room temperature spin Hall angle of Fe/β-PdBi2, = 0.037. This value is one order of magnitude larger than that of reported conventional 2 superconductors, and is comparable to that of the best SOC metals and topological insulators. Our results provide an avenue for developing superconductor-based spintronic applications.