Chemical Structure-Biological Activity Relationships in the Phenoxyacetic Acid Series

Angular Dependence of the Interaction Energy Between the N Lone Pair of Amines and a Proton: Relevance to Drug-Receptor Systems

“…Many hormones and drugs elicit their biological response through interactions with specific receptors (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). These interactions are typically weak, reversible, and specific (11) and, in addition, do not involve covalent bonding (1,2,8,9).…”