ChemInform Abstract: A Manganese Catalyst for Highly Reactive Yet Chemoselective Intramolecular C(sp3)—H Amination.

Abstract

A novel manganese C‐H amination catalyst is easily synthesized in one step from commercially available materials.

Silver Catalyzed Site-Selective C(sp3)−H Bond Amination of Secondary over Primary C(sp3)−H Bonds

“…Among these methods, direct selective amination of inert aliphatic C(sp 3 )–H bonds, which exists widely in nature, not only meets the requirements of “atomic economy”, but is the most simple and efficient strategy. Inexpensive metal-catalyzed nitrene transfer reactions have become an effective C-N bond formation method, following the contributions of Schomaker [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 ], Liu [ 29 , 30 , 31 ], White [ 32 , 33 , 34 ], Zhang [ 35 , 36 , 37 , 38 ], Che [ 39 , 40 , 41 ], and others [ 42 , 43 , 44 , 45 , 46 ].…”