ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe₂O₃ and Mesoporous Fluorescent ZnO.

Abstract

A Multifunctional Nanocomposite of Magnetic -Fe 2O3 and Mesoporous Fluorescent ZnO. -The title nanocomposite is prepared by dispersing -Fe 2O3 and mesoporous ZnO in EtOH under sonication (250 W, 10 min) before mixing and refluxing (80 C, 4 h). Drug conjugation by ultrasonication and release characteristics of the title nanocomposite reveal that mesoporous ZnO takes up 86% of the anticancer drug daunorubicin hydrochloride within 60 min and that the -Fe 2O3 helps in separating the drug carrier from solution. Drug loading hereby is monitored by the change in adsorbance of the drug solution at 483 nm via a UV/vis spectrophotometer. Release of the drug with and without ultrasonic irradiation indicates that in both cases the amount is higher under acidic pH. The presence of a high saturation magnetization along with visible emission makes this composite an ideal multifunctional material for drug delivery studies. -(MAITI, D.; MUKHOPADHYAY, S.; CHANDRA MOHANTA, S.; SAHA, A.; SUJATHA DEVI*, P.; J. Alloys Compd. 653 (2015) 187-194, http://dx.