ChemInform Abstract: A New Route for the Synthesis of Ozagrel Hydrochloride.

Abstract

A New Route for the Synthesis of Ozagrel Hydrochloride. -Starting from p-tolualdehyde, a new cost efficient synthetic route to title compound (VI), a highly selective thromboxane A2 inhibitor, is described. The overall yield is 72% compared to 34% realized in a previously reported method. -(YU, C.; ZHAO, B.; ZHAO, Y.; LIN*, J.; Org.