ChemInform Abstract: A New Synthesis of the Benzo[c]phenanthridines Nornitidine (Va), Noravicine (Vb), and Isodecarine (IX) Based on a Microwave‐Assisted Electrocyclic Reaction of the Aza 6π‐Electron System.

Abstract

A New Synthesis of the Benzo[c]phenanthridines Nornitidine (Va), Noravicine (Vb), and Isodecarine (IX) Based on a Microwave-Assisted Electrocyclic Reaction of the Aza 6π-Electron System. -The new strategy is based on the Suzuki--Miyaura reaction of 2-bromobenzaldehydes (II) with pinacol borate (I) and microwave-assisted electrocyclization of oximes (IIIa,b) and (VII). -(KOHNO, K.; AZUMA, S.; CHOSHI, T.; NOBUHIRO, J.; HIBINO*, S.; Tetrahedron Lett. 50 (2009) 5, 590-592; Fac. Pharm. Pharm. Sci., Grad. Sch. Pharm. Pharm. Sci., Fukuyama Univ., Fukuyama, Hiroshima 729-02, Japan; Eng.) -Mais 19-184