ChemInform Abstract: A One‐Pot, Stereoselective Synthesis of (Z)‐2‐Sulfonyl‐Substituted 1,3‐Enynes by Hydrostannylation‐Stille Tandem Reaction of Acetylenic Sulfones.

Abstract

Sulfones Q 0600A One-Pot, Stereoselective Synthesis of (Z)-2-Sulfonyl-Substituted 1,3-Enynes by Hydrostannylation-Stille Tandem Reaction of Acetylenic Sulfones. -Title compounds (III) are stereoselectively synthesized in a one-pot procedure by Pd-catalyzed hydrostannylation of acetylenic sulfones (I) followed by Stille coupling with alkynyl bromides (II). The tandem reaction does not occur in the absence of CuI and depends on the right combination of solvents. -(ZHAO, H.; ZHANG, H.-Y.; CAI*, M.