ChemInform Abstract: A Simple Preparation of Ethyl 2,5‐Dimethylfuran‐3‐carboxylate and 2,5‐Dimethylfuran‐3,4‐dicarboxylic Acid from Diethyl 2,3‐Diacetylsuccinate.

Abstract

Furan derivatives R 0060A Simple Preparation of Ethyl 2,5-Dimethylfuran-3-carboxylate and 2,5-Dimethylfuran-3,4-dicarboxylic Acid from Diethyl 2,3-Diacetylsuccinate. -The products can be easily prepared by thermal or microwave-promoted Paal-Knorr cyclization. The outcome of the reaction can be simply influenced by adjusting the HCl concentration. Diester (II) is only obtained under microwave irradiation.