ChemInform Abstract: Amino Acids. Part 4. Enantioselective Synthesis of N‐Substituted α‐Amino Carboxylic Acids from α‐Hydroxy Carboxylic Acids.

Abstract

The (S)‐carboxylates (I) react with the corresponding prim. and sec. amines (III), (VII), (VIII) or (X) to give the N‐substituted (R)‐amino carboxylates (IV), (IX), or (XI).