ChemInform Abstract: An Approach to Preparation of trans‐DHQs via Ring‐Opening of meso‐N‐Sulfonylaziridines.

Abstract

An Approach to Preparation of trans-DHQs via Ring-Opening of meso-N-Sulfonylaziridines. -The ring opening of aziridine derivative (I) is studied. Enantiomeric excess values up to 40% are obtained if the ring opening with Tms-CN is performed in the presence of chiral ligands. Aziridine (I) can be used as starting material for the synthesis of trans-octahydroquinoline (XIII). -(NOLSOEE, J.; RIEGERT, D.; MUELLER*, P.; TANNER, D.; Collect. Czech. Chem. Commun. 76 (2011) 7, 815-828, http://dx.doi.org/10.1135/cccc2011013 ; Dep. Org. Chem., Univ. Geneva, CH-1211 Geneva 4, Switz.; Eng.) -M. Bohle 43-143