ChemInform Abstract: An Enzymatic Entry to Enantiopure β‐Amino Acids.

Abstract

aminocarboxylic acidsaminocarboxylic acids (hydrazinocarboxylic acids) and esters (benzene compounds) Q 0440 -156An Enzymatic Entry to Enantiopure β-Amino Acids.-Optically pure enantiomers of β-amino acids such as (II), which are of interest for the synthesis of peptides or β-lactam antibiotics, are prepared by penicillin acylase catalyzed resolution of their racemic N-phenylacetyl derivatives (I). -(SOLOSHONOK, V. A.; SVEDAS, V. K.; KUKHAR, V. P.; KIRILENKO, A. G.; RYBAKOVA, A. V.; SOLODENKO, V. A.; FOKINA, N. A.; KOGUT, O. V.; GALAEV, I. Y.; KOZLOVA, E. V.; SHISHKINA, I. P.; GALUSHKO, S. V.; Synlett (1993) 5, 339-341; Inst. Bioorg. Petrol Chem., Ukrainian Acad. Sci., 253160 Kiev. Ukraine; EN)